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View Structure Prediction Details

Protein: ACAP1_ARATH
Organism: Arabidopsis thaliana
Length: 476 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACAP1_ARATH.

Description E-value Query
Range
Subject
Range
gi|50733649 - gi|50733649|ref|XP_418936.1| PREDICTED: similar to adenylyl cyclase-associated protein 2; 2810452G09...
664.0 [0..1] [473..1]

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Predicted Domain #1
Region A:
Residues: [1-231]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEDLIKRLE AAVTRLEGIS SNGGGVVSLS RGGDFSSAAG IDIASSDPSI LAYEDLISQC  60
   61 VGRALTAAEK IGGPVLDVTK IVAEAFASQK ELLVRIKQTQ KPDLAGLAGF LKPLNDVTMK 120
  121 ANAMTEGKRS DFFNHLKAAC DSLSALAWIA FTGKDCGMSM PIAHVEESWQ MAEFYNNKVL 180
  181 VEYRNKDADH VEWAKALKEL YLPGLREYVK SHYPLGPVWN ASGKPASAPA K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 65.39794
Match: 1tjfA
Description: The crystal structure of the N-terminal domain of CAP indicates variable oligomerisation
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 5.81884714997094 bayes_pls_golite062009
cytoskeletal protein binding 4.39652693178112 bayes_pls_golite062009
adenylate cyclase binding 2.08284870927262 bayes_pls_golite062009
binding 1.8340549733034 bayes_pls_golite062009
enzyme binding 1.53072876683435 bayes_pls_golite062009
protein binding 0.871734119777931 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [232-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPPGAPAPPP APLFSAESSK PSSSSNQKQG MSAVFQQLSS GAVTSGLRKV TDDMKTKNRA  60
   61 DRSGAVSAVE KETRTSKPAF SKTG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [316-476]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPKMELQMGR KWAVENQIGK KDLVISECDS KQSVYIYGCK DSVLQIQGKV NNITIDKCTK  60
   61 VGVVFTDVVA AFEIVNCNNV EVQCQGSAPT VSVDNTTGCQ LYLNKDSLET AITTAKSSEI 120
  121 NVMVPGATPD GDWVEHALPQ QYNHVFTEGK FETTPVSHSG A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.221849
Match: 1k8fA
Description: C-terminal domain of adenylylcyclase associated protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 4.94933252861141 bayes_pls_golite062009
cytoskeletal protein binding 4.21664682046338 bayes_pls_golite062009
actin monomer binding 2.04365563273836 bayes_pls_golite062009
binding 1.57578562719958 bayes_pls_golite062009
adenylate cyclase binding 1.13353932343086 bayes_pls_golite062009
enzyme binding 0.705135358375 bayes_pls_golite062009
protein binding 0.651719649953198 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle