YRC Public Data Repository - Protein Structure Prediction

Protein:	NCS1_ARATH
Organism:	Arabidopsis thaliana
Length:	599 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NCS1_ARATH.

Description	E-value	Query Range	Subject Range
gi\|50292087, gi\|... - gi\|50292087\|ref\|XP_448476.1\| unnamed protein product [Candida glabrata], gi\|49527788\|emb\|CAG61437.1\|... gi\|49527788 - gi\|49527788\|emb\|CAG61437.1\| unnamed protein product [Candida glabrata]	252.0	[0..44]	[598..42]
gi\|238482071, gi... - gi\|238482071\|ref\|XP_002372274.1\| amino acid permease (Gap1), putative [Aspergillus flavus NRRL3357],... gi\|169765514 - gi\|169765514\|ref\|XP_001817228.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83765083 - gi\|83765083\|dbj\|BAE55226.1\| unnamed protein product [Aspergillus oryzae]	244.0	[0..76]	[598..25]
gi\|50753798 - gi\|50753798\|ref\|XP_414136.1\| PREDICTED: similar to system asc amino acid transporter Asc-1 [Gallus g...	243.0	[0..2]	[560..237]
gi\|49642354 - gi\|49642354\|emb\|CAH00316.1\| KLLA0D03454p [Kluyveromyces lactis] gi\|50306493, gi\|... - gi\|50306493\|ref\|XP_453220.1\| unnamed protein product [Kluyveromyces lactis], gi\|49642354\|emb\|CAH0031...	241.0	[0..29]	[592..19]
AGP1_SACBA - General amino acid permease AGP1 OS=Saccharomyces bayanus GN=AGP1 PE=3 SV=1 AGP1_SACU7 - General amino acid permease AGP1 OS=Saccharomyces uvarum (strain ATCC 76518 / CBS 7001 / CLIB 283 / ...	241.0	[0..52]	[598..41]
gi\|114193057, gi... - gi\|115395202\|ref\|XP_001213488.1\| general amino-acid permease GAP1 [Aspergillus terreus NIH2624], gi\|...	239.0	[0..68]	[598..9]
gi\|42552670, gi\|... - gi\|46121799\|ref\|XP_385453.1\| hypothetical protein FG05277.1 [Gibberella zeae PH-1], gi\|42552670\|gb\|E...	239.0	[0..91]	[596..3]
gi\|49647803, gi\|... - gi\|50548931\|ref\|XP_501936.1\| YALI0C17237p [Yarrowia lipolytica], gi\|49647803\|emb\|CAG82256.1\| unnamed... gi\|49647803 - gi\|49647803\|emb\|CAG82256.1\| YALI0C17237p [Yarrowia lipolytica]	238.0	[0..126]	[583..104]
GNP1_YEAST - High-affinity glutamine permease OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GNP1 PE... GNP1 - High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is ful...	236.0	[0..70]	[599..89]

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Predicted Domain #1

Region A:
Residues: [1-125]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSNCLSLSL HLNLHPHKHN RHSLSSLRSR TKAKLYQHVS FTDSSHKSSY TSCVSTFDIQ  60
   61 RKSSKHYELG KHSFSPILPG DNLVLSRSGV IRPRLSAMTG SEINDHGYDE SQFDPSLTND 120
  121 DLKPT

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [126-599]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPSQRTFSWL DMSSLWIGLV VGVPTYYLAG SLVDLGMAWW QGIATVVTAN LILLVPLVLT  60
   61 AQPGTLYGIS FPVLARSSFG IRGAHIPTLL RALVGCGWYG IETWIGGEAI FLLLPGHIKK 120
  121 SALSHTLPWL GTSPLEFSCF IVFWLAQLCI VWRGMDGIRK LEKYSAPILI SLTSCLLAWS 180
  181 YLKAGGFGHM LSLSSKLTSA QFWTLFFPSL TANISFWATL ALNIPDFSRF AKSQTDQIIG 240
  241 QVGLPVFMGL FTFVGVAVTS STSIIFGRVI SNPIELLGQI GGLATTLLAI VGISLATLTT 300
  301 NIAANVVAPA NALVNLNPKF FTFGRGAFLT AVLGIVFQPW RLLKSSESFV YTWLIGYSAL 360
  361 LGPIGGIILV DYYLIKKMKL NIGDLYSLSP SGEYYFSKGY NVAAVVALVA GIIPVVPGFL 420
  421 HKISALSKIS NGFVVVYDNA LFFSFIIAGF VYWIIMSRLG RKQSSLSSSS HPLL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.69897
Match:	2a65A
Description:	Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits