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View Structure Prediction Details

Protein: IRE_ARATH
Organism: Arabidopsis thaliana
Length: 1168 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

No multiple sequence alignment data found for IRE_ARATH.

Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTTEPSPEN DRDPQPTTIS TPTSTNAKLL KKIPAIPFRH SDKEGEDEQA KTDEVTTELA  60
   61 GEGPMSHDSP EILAPSSLGL NHIRTKSSPA PSP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [94-165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRFSSATPLI SPGQDDKDVA KEKPRVGVVD ARADARARWP IPPHQPDQGK KVQWSQSKSQ  60
   61 RVPANSNPGV ES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [166-394]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 THVGLAKETQ SPRFQAILRV TSGRKKKAHD IKSFSHELNS KGVRPFPVWR SRAVGHMEEI  60
   61 MAAIRTKFDK QKEDVDADLG VFAGYLVTTL ESTPESNKEL RVGLEDLLVE ARQCATMPAS 120
  121 EFWLKCEGIV QKLDDKRQEL PMGGLKQAHN RLLFILTRCN RLVQFRKESG YVEEHILGMH 180
  181 QLSDLGVYPE QMVEISRQQD LLREKEIQKI NEKQNLAGKQ DDQNSNSGA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [395-536]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGVEVNTARS TDSTSSNFRM SSWKKLPSAA EKNRSLNNTP KAKGESKIQP KVYGDENAEN  60
   61 LHSPSGQPAS ADRSALWGFW ADHQCVTYDN SMICRICEVE IPVVHVEEHS RICTIADRCD 120
  121 LKGINVNLRL ERVAESLEKI LE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [537-747]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SWTPKSSVTP RAVADSARLS NSSRQEDLDE ISQRCSDDML DCVPRSQNTF SLDELNILNE  60
   61 MSMTNGTKDS SAGSLTPPSP ATPRNSQVDL LLSGRKTISE LENYQQINKL LDIARSVANV 120
  121 NVCGYSSLDF MIEQLDELKY VIQDRKADAL VVETFGRRIE KLLQEKYIEL CGLIDDEKVD 180
  181 SSNAMPDEES SADEDTVRSL RASPLNPRAK D

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1dsyA
Description: C2 domain from protein kinase c (alpha)
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [748-1053]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTSIEDFEII KPISRGAFGR VFLAKKRATG DLFAIKVLKK ADMIRKNAVE SILAERNILI  60
   61 SVRNPFVVRF FYSFTCRENL YLVMEYLNGG DLFSLLRNLG CLDEDMARIY IAEVVLALEY 120
  121 LHSVNIIHRD LKPDNLLINQ DGHIKLTDFG LSKVGLINST DDLSGESSLG NSGFFAEDGS 180
  181 KAQHSQGKDS RKKHAVVGTP DYLAPEILLG MGHGKTADWW SVGVILFEVL VGIPPFNAET 240
  241 PQQIFENIIN RDIPWPNVPE EISYEAHDLI NKLLTENPVQ RLGATGAGEV KQHHFFKDIN 300
  301 WDTLAR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.522879
Match: 1z5mA
Description: Crystal Structure Of N1-[3-[[5-bromo-2-[[3-[(1-pyrrolidinylcarbonyl)amino]phenyl]amino]-4-pyrimidinyl]amino]propyl]-2,2-dimethylpropanediamide Complexed with Human PDK1
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [1054-1168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKAMFVPSAE PQDTSYFMSR YIWNPEDENV HGGSDFDDLT DTCSSSSFNT QEEDGDECGS  60
   61 LAEFGNGPNL AVKYSFSNFS FKNLSQLASI NYDLVLKNAK ESVEASNQSA PRPET

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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