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View Structure Prediction Details

Protein: CDPK4_ARATH
Organism: Arabidopsis thaliana
Length: 501 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDPK4_ARATH.

Description E-value Query
Range
Subject
Range
CDPKB_ARATH - Calcium-dependent protein kinase 11 OS=Arabidopsis thaliana GN=CPK11 PE=1 SV=2
411.0 [0..1] [487..1]

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Predicted Domain #1
Region A:
Residues: [1-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKPNPRRPS NSVLPYETPR LRDHYLLGKK LGQGQFGTTY LCTEKSSSAN YACKSIPKRK  60
   61 LVCREDYEDV WREIQIMHHL SEHPNVVRIK GTYEDSVFVH IVMEVCEGGE LFDRIVSKGC 120
  121 FSEREAAKLI KTILGVVEAC HSLGVMHRDL KPENFLFDSP SDDAKLKATD FGLSVFYKPG 180
  181 QYLYDVVGSP YYVAPEVLKK CYGPEIDVWS AGVILYILLS GVPPFWAETE SGIFRQILQG 240
  241 KIDFKSDPWP TISEGAKDLI YKMLDRSPKK RISAHEALCH PWIVDEHAAP DKPLDPAVLS 300
  301 RLKQFSQMNK IKKMALRVIA ERL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.39794
Match: 2bdwA
Description: Crystal Structure of the Auto-Inhibited Kinase Domain of Calcium/Calmodulin Activated Kinase II
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [324-501]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEEEIGGLKE LFKMIDTDNS GTITFEELKA GLKRVGSELM ESEIKSLMDA ADIDNSGTID  60
   61 YGEFLAATLH INKMEREENL VVAFSYFDKD GSGYITIDEL QQACTEFGLC DTPLDDMIKE 120
  121 IDLDNDGKID FSEFTAMMKK GDGVGRSRTM RNNLNFNIAE AFGVEDTSST AKSDDSPK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.0
Match: 1s6iA
Description: Ca2+-regulatory region (CLD) from soybean calcium-dependent protein kinase-alpha (CDPK) in the presence of Ca2+ and the junction domain (JD)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.74623080162785 bayes_pls_golite062009
cation binding 1.24254937475287 bayes_pls_golite062009
metal ion binding 1.24254937475287 bayes_pls_golite062009
ion binding 1.23493891392859 bayes_pls_golite062009
protein binding 1.16246005294206 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.05536109719637 bayes_pls_golite062009
kinase activity 1.01041521285233 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.850539727259368 bayes_pls_golite062009
structural molecule activity 0.800850121197479 bayes_pls_golite062009
transferase activity 0.297929823471296 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle