YRC Public Data Repository - Protein Structure Prediction

Protein:	P2C43_ARATH
Organism:	Arabidopsis thaliana
Length:	422 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for P2C43_ARATH.

Description	E-value	Query Range	Subject Range
gi\|51971549 - gi\|51971549\|dbj\|BAD44439.1\| putative protein phosphatase-2C [Arabidopsis thaliana]	278.0	[0..39]	[422..1]
gi\|51704009, gi\|... - gi\|89268278\|emb\|CAJ81612.1\| protein phosphatase 1B, magnesium-dependent, beta isoform [Xenopus tropi...	273.0	[0..96]	[421..1]
gi\|17391324, gi\|... - gi\|94403183\|ref\|XP_990021.1\| PREDICTED: similar to Protein phosphatase 2C isoform beta (PP2C-beta) i...	273.0	[0..96]	[421..1]
gi\|109102776 - gi\|109102776\|ref\|XP_001111545.1\| PREDICTED: protein phosphatase 1B (formerly 2C), magnesium-dependen...	272.0	[0..96]	[422..1]
gi\|73969501 - gi\|73969501\|ref\|XP_864293.1\| PREDICTED: similar to Protein phosphatase 2C beta isoform (PP2C-beta) i...	272.0	[0..96]	[421..1]
gi\|49256034, gi\|... - gi\|49256034\|gb\|AAH71108.1\| MGC81273 protein [Xenopus laevis], gi\|148227634\|ref\|NP_001085342.1\| MGC81...	272.0	[0..96]	[421..1]

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Predicted Domain #1

Region A:
Residues: [1-95]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRTSKASVTQ TWLLYTQLCL WKDLIIRYVR QIIRRAKSML FSQNMVADSA EISVIDVKSH  60
   61 LSVAKDPSNF QIAEIRIHDS ICIDIPSSEE TPLLE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.868	d.18.1	ssDNA-binding transcriptional regulator domain
View	Download	0.613	d.24.1	Pili subunits
View	Download	0.578	d.38.1	Thioesterase/thiol ester dehydrase-isomerase
View	Download	0.573	a.7.12	Description not found.
View	Download	0.556	a.2.11	Fe,Mn superoxide dismutase (SOD), N-terminal domain
View	Download	0.493	a.2.11	Fe,Mn superoxide dismutase (SOD), N-terminal domain
View	Download	0.457	d.225.1	Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
View	Download	0.441	f.36.1	Neurotransmitter-gated ion-channel pransmembrane pore
View	Download	0.418	a.24.17	Group V grass pollen allergen

Predicted Domain #2

Region A:
Residues: [96-422]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIKSCSATTI EEHVTEFVPN ISSGSYADKG DYREYMEDEH ICIDDLSDHL GSSFYRFPVP  60
   61 MAFYGVFDGH GGSDASQYIK ENAMSLFFED AVFRQSPSVV DSLFLKELET SHREAYRLAD 120
  121 LAMEDERIVS SSCGTTALTA LVIGRHLMVA NVGDCRAVLC RKGKAVDMSF DHKSTFEPER 180
  181 RRVEDLGGYF EGEYLYGDLA VTRALGDWSI KRFSPLGESL SPLISDPDIQ QMILTEEDEF 240
  241 LIMGCDGVWD VMTSQYAVTF VRQGLRRHGD PRRCAMELGR EALRLDSSDN VTVVVICFSS 300
  301 SPAPQRRRIR FCVSDEARAR LQTMLEG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	71.09691
Match:	1a6qA
Description:	CRYSTAL STRUCTURE OF THE PROTEIN SERINE/THREONINE PHOSPHATASE 2C AT 2 A RESOLUTION
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits