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View Structure Prediction Details

Protein: PKP4_ARATH
Organism: Arabidopsis thaliana
Length: 710 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PKP4_ARATH.

Description E-value Query
Range
Subject
Range
gi|108797363, gi... - gi|108797363|ref|YP_637560.1| pyruvate kinase [Mycobacterium sp. MCS], gi|108767782|gb|ABG06504.1| p...
gi|92440454, gi|... - gi|92915197|ref|ZP_01283821.1| Pyruvate kinase [Mycobacterium sp. KMS], gi|92440454|gb|EAS98297.1| P...
520.0 [0..94] [709..2]

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Predicted Domain #1
Region A:
Residues: [1-193]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVGLDSSHLL RDKILCFSSR SHINNQHKKT SYALSLNHMK LPIQRTLAFA LARGKGEAES  60
   61 FSRLEATFGD NTSTECTWSF DFPDSKDAMS HLKSEADLSG SNGANNVASV IEKLNALRSH 120
  121 LLAAEKWNAS QLHLCDSKYL ECATNLVHYM ALRSLDIEQL NSHLASLGLS SLDNNNLDVL 180
  181 AHLNASINLL MND

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [194-342]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNAVTESWTN VYPKGKSTKK NDKGRVLSYK ESLLGKLREG RSTHIMVTIG EEATLSETFI  60
   61 TDILKAGTSV IRINCAHGDP SIWGEIIKRV RRTSQMLEMP CRVHMDLAGP KLRTGTLKPG 120
  121 PCVMKISPKK DAYGNVVSPA LVWLCLTGT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.6
Match: 1liuA
Description: Pyruvate kinase (PK); Pyruvate kinase, N-terminal domain; Pyruvate kinase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [343-710]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPPAHVSPDA TISVQGQDFL AGLQIGDSIR LCDARGRKRR LKISKEFHVF NSTGFVAECF  60
   61 DTAYIESGTE LSVKGKKGRR LVGRVVDVPP KESFVRLKVG DLLVITREGS LDEPSVTVPG 120
  121 AHRLTCPSGY LFDSVKPGET IGFDDGKIWG VIKGTSPSEV IVSITHARPK GTKLGSEKSI 180
  181 NIPQSDIHFK GLTSKDIKDL DYVASHADMV GISFIRDVHD ITVLRQELKK RKLDDLGIVL 240
  241 KIETKSGFKN LSLILLEAMK CSNPLGIMIA RGDLAVECGW ERLANMQEEI IAICKAARVP 300
  301 VIMATQVLES LVKSGVPTRA EITDAANAKR ASCVMLNKGK NIVEAVSMLD TILHTKLIYK 360
  361 KSDSENLH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 126.0
Match: 1zjhA
Description: Structure of human muscle pyruvate kinase (PKM2)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle