YRC Public Data Repository - Protein Structure Prediction

Protein:	AGO7_ARATH
Organism:	Arabidopsis thaliana
Length:	990 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AGO7_ARATH.

Description	E-value	Query Range	Subject Range
gi\|62649646 - gi\|62649646\|ref\|XP_233544.3\| PREDICTED: similar to eukaryotic translation initiation factor 2C, 1 [R...	908.0	[0..9]	[989..64]
gi\|73977123 - gi\|73977123\|ref\|XP_532563.2\| PREDICTED: similar to eukaryotic translation initiation factor 2C, 1 [C...	894.0	[0..37]	[989..89]
AGO2_RABIT - Protein argonaute-2 (Fragment) OS=Oryctolagus cuniculus GN=AGO2 PE=1 SV=2	866.0	[0..147]	[989..3]
gi\|66792511 - gi\|66792511\|gb\|AAH96465.1\| Eif2c2 protein [Mus musculus]	865.0	[0..103]	[989..2]
EIF2C2 - eukaryotic translation initiation factor 2C, 2 gi\|182888339 - gi\|182888339\|gb\|AAI60104.1\| Eukaryotic translation initiation factor 2C, 2 [synthetic construct]	865.0	[0..147]	[989..22]
gi\|114555730 - gi\|114555730\|ref\|XP_524663.2\| PREDICTED: eukaryotic translation initiation factor 2C, 4 [Pan troglod...	863.0	[0..44]	[989..96]

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Predicted Domain #1

Region A:
Residues: [1-150]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEKTHHHHH STNKHIPSSK SRTPLLHKPY HHHVQTNPPP FLLHPSSHQN LNLVASNLPS  60
   61 SYYYYYYCYF YSQFHNSLPP PPPPHLLPLS PPLPPLLPLP PPHSMTRFHK SLPVSQVVER 120
  121 KQQHQQKKKI QVSNNKVSGS IAIEEAALVV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.522879
Match:	1y0fA
Description:	No description for 1y0fA was found.

Predicted Domain #2

Region A:
Residues: [151-990]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKRPDFGGQD GSVIYLLANH FLVKFDSSQR IYHYNVEISP QPSKEIARMI KQKLVETDRN  60
   61 SFSGVVPAFD GRQNIYSPVE FQGDRLEFFV NLPIPSCKAV MNYGDLREKQ PQKKIEKLFR 120
  121 VNMKLVSKFD GKEQRKEGED WAPLPPEYIH ALDVILRENP MEKCTSIGRS FYSSSMGGSK 180
  181 EIGGGAVGLR GFFQSLRHTQ QGLALNMDLS ITAFHESIGV IAYLQKRLEF LTDLPRNKGR 240
  241 ELSLEEKREV EKALKNIRVF VCHRETVQRY RVYGLTEEIT ENIWFPDREG KYLRLMSYFK 300
  301 DHYGYEIQFK NLPCLQISRA RPCYLPMELC MICEGQKFLG KLSDDQAAKI MKMGCQKPNE 360
  361 RKAIIDKVMT GSVGPSSGNQ TREFNLEVSR EMTLLKGRIL QPPKLKLDRP RNLKESKVFK 420
  421 GTRIERWALM SIGGSSDQKS TIPKFINELT QKCEHLGVFL SKNTLSSTFF EPSHILNNIS 480
  481 LLESKLKEIQ RAASNNLQLI ICVMEKKHKG YGDLKRISET RIGVVTQCCL YPNITKLSSQ 540
  541 FVSNLALKIN AKIGGSMTEL YNSIPSHIPR LLRPDEPVIF MGADVTHPHP FDDCSPSVAA 600
  601 VVGSINWPEA NRYVSRMRSQ THRQEIIQDL DLMVKELLDD FYKAVKKLPN RIIFFRDGVS 660
  661 ETQFKKVLQE ELQSIKTACS KFQDYNPSIT FAVVQKRHHT RLFRCDPDHE NIPPGTVVDT 720
  721 VITHPKEFDF YLCSHLGVKG TSRPTHYHIL WDENEFTSDE LQRLVYNLCY TFVRCTKPIS 780
  781 IVPPAYYAHL AAYRGRLYIE RSSESNGGSM NPSSVSRVGP PKTIPLPKLS DNVKNLMFYC 840
  841

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.30103
Match:	1u04A
Description:	Crystal structure of full length Argonaute from Pyrococcus furiosus
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.2	NCBI nr	03/2009
PSI-BLAST	2.2.22	FFAS	ffas03
PDB	10/2008	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits