YRC Public Data Repository - Protein Structure Prediction

Protein:	PHB4_ARATH
Organism:	Arabidopsis thaliana
Length:	279 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PHB4_ARATH.

Description	E-value	Query Range	Subject Range
PHB_CHICK - Prohibitin OS=Gallus gallus GN=PHB PE=1 SV=1	232.0	[0..6]	[275..1]
gi\|21592895 - gi\|21592895\|gb\|AAM64845.1\| prohibitin, putative [Arabidopsis thaliana]	231.0	[0..1]	[279..1]
gi\|58979188 - gi\|58979188\|gb\|AAW83328.1\| mitochondrial prohibitin 1 [Petunia x hybrida]	229.0	[0..1]	[279..1]
gi\|89272030, gi\|... - gi\|89272810\|emb\|CAJ82042.1\| prohibitin [Xenopus tropicalis], gi\|89272030\|emb\|CAJ83243.1\| prohibitin ...	228.0	[0..6]	[275..1]
PHB_RAT - Prohibitin OS=Rattus norvegicus GN=Phb PE=1 SV=1 tr\|G3HJP6\|G3HJP6... - Prohibitin OS=Cricetulus griseus GN=I79_010895 PE=4 SV=1 PHB_MOUSE - Prohibitin OS=Mus musculus GN=Phb PE=1 SV=1	228.0	[0..6]	[275..1]
gi\|33286931, gi\|... - gi\|41351079\|gb\|AAH65895.1\| Phb protein [Danio rerio], gi\|41152028\|ref\|NP_958454.1\| prohibitin [Danio...	227.0	[0..8]	[275..2]
gi\|61362617, gi\|... - gi\|61362624\|gb\|AAX42254.1\| prohibitin [synthetic construct], gi\|61362617\|gb\|AAX42253.1\| prohibitin [... HGNC:8912\|MIM:17... - null PHB - prohibitin PHB_BOVIN - Prohibitin OS=Bos taurus GN=PHB PE=2 SV=1 gi\|158906128, gi... - gi\|160333845\|ref\|NP_001103918.1\| prohibitin [Felis catus], gi\|158906128\|gb\|ABW82705.1\| prohibitin [F... gi\|158442066, gi... - gi\|158819069\|ref\|NP_001103649.1\| prohibitin [Canis lupus familiaris], gi\|158442066\|gb\|ABW38778.1\| pr... gi\|109114258, gi... - gi\|109114260\|ref\|XP_001093569.1\| PREDICTED: similar to prohibitin isoform 7 [Macaca mulatta], gi\|109... ENSCJAT00000014086 - null gi\|114666273, gi... - gi\|55646807\|ref\|XP_511949.1\| PREDICTED: prohibitin isoform 7 [Pan troglodytes], gi\|114666277\|ref\|XP_...	227.0	[0..6]	[275..1]
gi\|60829530 - gi\|60829530\|gb\|AAX36882.1\| prohibitin [synthetic construct]	227.0	[0..6]	[275..1]

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Predicted Domain #1

Region A:
Residues: [1-77]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSQQVAISF LTNLAKAAFG LGVAATALNS SLYTVDGGER AVLFDRFRGV LDQTVGEGTH  60
   61 FLIPYLQTPH IYDIRTK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.784	d.24.1	Pili subunits
View	Download	0.774	d.39.1	Dynein light chain 8 (DLC8)
View	Download	0.723	d.129.2	Phosphoglucomutase, C-terminal domain
View	Download	0.698	d.39.1	Dynein light chain 8 (DLC8)
View	Download	0.667	d.82.4	Description not found.
View	Download	0.650	d.129.2	Phosphoglucomutase, C-terminal domain
View	Download	0.634	d.58.18	Regulatory domain in the aminoacid metabolism
View	Download	0.625	c.51.1	Anticodon-binding domain of Class II aaRS
View	Download	0.623	c.52.2	tRNA splicing endonuclease, C-terminal domain
View	Download	0.572	d.39.1	Dynein light chain 8 (DLC8)
View	Download	0.557	c.52.2	tRNA splicing endonuclease, C-terminal domain
View	Download	0.419	a.163.1	Crustacean CHH/MIH/GIH neurohormone
View	Download	0.376	d.58.3	Protease propeptides/inhibitors
View	Download	0.333	d.52.7	Ribosome-binding factor A, RbfA
View	Download	0.317	d.150.1	4'-phosphopantetheinyl transferase

Predicted Domain #2

Region A:
Residues: [78-180]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PHTFSSKSGT KDLQMVNLTL RVLFRPEVSR LPYIFQTLGL EYDEKVLPSI GNEVLKAVVA  60
   61 NFNADQLLTE RPQVSALVRD ALIKRAREFN IELDDIAITH LSY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11.69897
Match:	1winA
Description:	Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [181-279]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAEFSRAVEA KQVAQQEAER SKFVVMKADQ ERRAAVIRAE GESEAAQLIS DATAKAGMGL  60
   61 IELRRIEASR EVAATLARSP NVAYLPGGQS MLFNLNPGR

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.774	a.24.17	Group V grass pollen allergen
View	Download	0.774	a.24.17	Group V grass pollen allergen
View	Download	0.735	a.7.6	Ribosomal protein S20
View	Download	0.735	a.7.6	Ribosomal protein S20
View	Download	0.650	a.158.1	F-box domain
View	Download	0.650	a.158.1	F-box domain
View	Download	0.606	a.216.1	Description not found.
View	Download	0.578	f.36.1	Neurotransmitter-gated ion-channel pransmembrane pore
View	Download	0.578	f.36.1	Neurotransmitter-gated ion-channel pransmembrane pore
View	Download	0.541	d.58.47	Hypothetical protein VC0424

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits