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View Structure Prediction Details

Protein: DNMT2_ARATH
Organism: Arabidopsis thaliana
Length: 1512 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

No multiple sequence alignment data found for DNMT2_ARATH.

Predicted Domain #1
Region A:
Residues: [1-150]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METKVGKQKK RSVDSNDDVS KERRPKRAAA CRNFKEKPLR ISDKSETVEA KKEQNVVEEI  60
   61 VAIQLTSSLE SNDDPRPNRR LTDFVLHNSD GVPQPVEMLE LGDIFLEGVV LPLGDDKNEE 120
  121 KGVRFQSFGR VENWNISGYE DGSPGIWIST 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [151-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALADYDCRKP ASKYKKIYDY FFEKACACVE VFKSLSKNPD TSLDELLAAV ARSMSGSKIF  60
   61 SSGGAIQEFV ISQGEFIYNQ LAGLDETAKN HETCFVENSV LVSLRDHES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [260-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKIHKALSNV ALRIDESQLV KSDHLVDGAE AEDVRYAKLI QEEEYRISME RSRNKRSSTT  60
   61 SASNKFYIKI NEHEI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [335-431]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANDYPLPSYY KNTKEETDEL LLFEPGYEVD TRDLPCRTLH NWALYNSDSR MISLEVLPMR  60
   61 PCAEIDVTVF GSGVVAEDDG SGFCLDDSES STSTQSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [432-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VHDGMNIFLS QIKEWMIEFG AEMIFVTLRT DMAWYRLGKP SKQYAPWFET VMKTVRVAIS  60
   61 IFNMLMRESR VAKLSYANVI KRLCGLEEND KAYISSKLLD VERYVVVHGQ IILQLFEEYP 120
  121 DKDIKRCPFV TGLASKMQDI HHTKWIIKRK KKILQKGKNL NPRAGLAHVV TRMKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.09691
Match: 2grcA
Description: No description for 2grcA was found.

Predicted Domain #6
Region A:
Residues: [607-667]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQATTTRLVN RIWGEFYSIY SPEVPSEAIH EVEEEEIEED EEEDENEEDD IEEEAVEVQK  60
   61 S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [668-908]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HTPKKSRGNS EDMEIKWNGE ILGETSDGEP LYGRALVGGE TVAVGSAVIL EVDDPDETPA  60
   61 IYFVEFMFES SDQCKMLHGK LLQRGSETVI GTAANERELF LTNECLTVHL KDIKGTVSLD 120
  121 IRSRPWGHQY RKENLVVDKL DRARAEERKA NGLPTEYYCK SLYSPERGGF FSLPRNDIGL 180
  181 GSGFCSSCKI KEEEEERSKT KLNISKTGVF SNGIEYYNGD FVYVLPNYIT KDGLKKGTSR 240
  241 R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.30103
Match: 1w4sA
Description: Crystal structure of the proximal BAH domain of polybromo
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [909-1065]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTLKCGRNVG LKAFVVCQLL DVIVLEESRK ASNASFQVKL TRFYRPEDIS EEKAYASDIQ  60
   61 ELYYSHDTYI LPPEALQGKC EVRKKNDMPL CREYPILDHI FFCEVFYDSS TGYLKQFPAN 120
  121 MKLKFSTIKD ETLLREKKGK GVETGTSSGI LMKPDEV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1066-1512]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKEMRLATLD IFAGCGGLSH GLEKAGVSNT KWAIEYEEPA GHAFKQNHPE ATVFVDNCNV  60
   61 ILRAIMEKCG DVDDCVSTVE AAELVAKLDE NQKSTLPLPG QADFISGGPP CQGFSGMNRF 120
  121 SDGSWSKVQC EMILAFLSFA DYFRPKYFLL ENVKKFVTYN KGRTFQLTMA SLLEIGYQVR 180
  181 FGILEAGTYG VSQPRKRVII WAASPEEVLP EWPEPMHVFD NPGSKISLPR GLHYDTVRNT 240
  241 KFGAPFRSIT VRDTIGDLPL VENGESKINK EYRTTPVSWF QKKIRGNMSV LTDHICKGLN 300
  301 ELNLIRCKKI PKRPGADWRD LPDENVTLSN GLVEKLRPLA LSKTAKNHNE WKGLYGRLDW 360
  361 QGNLPISITD PQPMGKVGMC FHPEQDRIIT VRECARSQGF PDSYEFSGTT KHKHRQIGNA 420
  421 VPPPLAFALG RKLKEALYLK SSLQHQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.154902
Match: 1dctA
Description: DNA methylase HaeIII
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle