YRC Public Data Repository - Protein Structure Prediction

Protein:	RSH2C_ARATH
Organism:	Arabidopsis thaliana
Length:	709 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RSH2C_ARATH.

Description	E-value	Query Range	Subject Range
gi\|56421113, gi\|... - gi\|56421113\|ref\|YP_148431.1\| GTP pyrophosphokinase (ppGpp synthetase) [Geobacillus kaustophilus HTA4...	697.0	[0..184]	[708..1]
gi\|10443847 - gi\|10443847\|gb\|AAG17607.1\|AF242653_1 ppGpp synthetase/hydrolase Rel [Geobacillus stearothermophilus]	697.0	[0..184]	[708..1]
gi\|20516195, gi\|... - gi\|20807650\|ref\|NP_622821.1\| guanosine polyphosphate pyrophosphohydrolase/synthetase [Thermoanaeroba... gi\|20807650 - gi\|20807650\|ref\|NP_622821.1\| Guanosine polyphosphate pyrophosphohydrolase/synthetase [Thermoanaeroba...	689.0	[0..192]	[708..2]
RSH2L_ARATH - Probable GTP diphosphokinase RSH2, chloroplastic OS=Arabidopsis thaliana GN=RSH2 PE=2 SV=1	688.0	[0..1]	[709..1]
gi\|83590516, gi\|... - gi\|83590516\|ref\|YP_430525.1\| (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA [Moorella ther...	687.0	[0..190]	[708..1]
gi\|241903868, gi... - gi\|241903868\|ref\|ZP_04788584.1\| (p)ppGpp synthetase I, SpoT/RelA [Thermoanaerobacter brockii subsp. ... gi\|76797241, gi\|... - gi\|76797241\|ref\|ZP_00779574.1\| RelA/SpoT protein [Thermoanaerobacter ethanolicus ATCC 33223], gi\|765...	686.0	[0..192]	[707..2]
gi\|78044718, gi\|... - gi\|78044718\|ref\|YP_361036.1\| GTP pyrophosphokinase [Carboxydothermus hydrogenoformans Z-2901], gi\|77...	680.0	[0..189]	[708..1]
gi\|82402728, gi\|... - gi\|82499307\|ref\|ZP_00884755.1\| RelA/SpoT protein [Caldicellulosiruptor saccharolyticus DSM 8903], gi...	678.0	[0..188]	[708..1]
gi\|89201354, gi\|... - gi\|89201354\|ref\|ZP_01180095.1\| RelA/SpoT protein [Bacillus cereus subsp. cytotoxis NVH 391-98], gi\|8...	674.0	[0..184]	[708..1]
gi\|110673259, gi... - gi\|110798612\|ref\|YP_696617.1\| GTP pyrophosphokinase [Clostridium perfringens ATCC 13124], gi\|1106732...	673.0	[0..192]	[708..2]

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Predicted Domain #1

Region A:
Residues: [1-180]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVATTIALY ASPPSSVCST PHQISCDLDL TSRSSSTSSS MASSPQKPIV GGLSSLFSSA  60
   61 SVKSSSSSSC SYSTGVDEFS SLRYDRSDDL KDLSFSSSFG YSPAKFVNSF RRDHQSPISV 120
  121 LHGPVSCSCS PPMRMSRDRN LDGSFRLGAS GLFNGFVRKA LGSCVDYEFG SDSVLVDELT 180
  181

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [181-563]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPMEVDTIKP YARDLLRRAQ LRHKIFNDES VIKAFYEAEK AHRGQMRASR DPYLQHCVET  60
   61 AMLLANIGAN STVVVAGLLH DTIDDSFMSY DYILRNFGAG VADLVEGVSK LSQLSKLARE 120
  121 NNTACKTVEA DRLHTMFLAM ADARAVLIKL ADRLHNMKTL YALSPVKQQR FAKETLEIFA 180
  181 PLANRLGIST WKVQLENLCF KHLYPNQHNE MSTMLEDSFD EAMITSAIEK LEQALKKAGI 240
  241 SYHVLCGRHK SLYSIYSKML KKKLTVDEIH DIHGLRLIVD NEGDCYKALG VVHSLWSEVP 300
  301 GKLKDYITHP KFNGYQSLHT VVMDNGTVPL EVQIRTQEMH LQAEFGFAAH WRYKEGGCKY 360
  361 SSFVLQMVEW ARWVVTWHCE AMS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	136.0
Match:	1vj7A
Description:	Crystal structure of the bifunctional catalytic fragment of RelSeq, the RelA/SpoT homolog from Streptococcus equisimilis.
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [564-709]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDRSSISSSD SIKPPCKFPS HSEDCPASYK PNSSQDGPVY VIVIENDKMS VQEFPASSTV  60
   61 SDLLSRAGPG SSRWSMYGIP AKEELRPRLN QIPVSDLKWK LKMGDVVELT PTIPDESLTE 120
  121 YREEIQRMYD RGLAFSRPGT MVGWGS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits