YRC Public Data Repository - Protein Structure Prediction

Protein:	HUA2_ARATH
Organism:	Arabidopsis thaliana
Length:	1392 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HUA2_ARATH.

Description	E-value	Query Range	Subject Range
gi\|73951793 - gi\|73951793\|ref\|XP_536224.2\| PREDICTED: similar to Wolf-Hirschhorn syndrome candidate 1 protein isof...	234.0	[0..1]	[596..139]
gi\|94374385, gi\|... - gi\|94374668\|ref\|XP_903405.2\| PREDICTED: Wolf-Hirschhorn syndrome candidate 1 isoform 6 [Mus musculus...	218.0	[0..1]	[596..180]
gi\|11385307 - gi\|11385307\|pir\|\|A35175 mucin 1 precursor, repetitive splice form A [validated] - human	217.0	[0..403]	[1392..24]
gi\|145332667, gi... - gi\|145332667\|ref\|NP_001078199.1\| structural constituent of cell wall [Arabidopsis thaliana], gi\|1199...	213.0	[0..205]	[1377..204]
gi\|70878483 - gi\|70878483\|gb\|EAN91735.1\| trans-sialidase, putative [Trypanosoma cruzi] gi\|71649745 - gi\|71649745\|ref\|XP_813586.1\| trans-sialidase [Trypanosoma cruzi strain CL Brener]	210.0	[0..3]	[935..812]
gi\|37930527, gi\|... - gi\|37930527\|gb\|AAP74661.1\| elicitor-like transglutaminase M81 [Phytophthora infestans], gi\|23505399\|...	204.0	[0..382]	[1388..512]
gi\|50758715 - gi\|50758715\|ref\|XP_417384.1\| PREDICTED: similar to KIAA1125 protein [Gallus gallus]	190.0	[0..19]	[927..433]
gi\|18025526, gi\|... - gi\|51518075\|ref\|YP_068003.1\| LF3 [Macacine herpesvirus 4], gi\|18025526\|gb\|AAK95470.1\| LF3 [cercopith...	186.0	[0..543]	[1384..12]
gi\|76666643 - gi\|76666643\|ref\|XP_613048.2\| PREDICTED: similar to Wolf-Hirschhorn syndrome candidate 1 protein isof...	186.0	[0..1]	[596..200]

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Predicted Domain #1

Region A:
Residues: [1-118]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPGRKRGAS KAKAKGQLVL GDLVLAKVKG FPAWPAKISR PEDWDRAPDP KKYFVQFFGT  60
   61 EEIAFVAPPD IQAFTSEAKS KLLARCQGKT VKYFAQAVEQ ICTAFEGLQN HKSNALGD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.69897
Match:	2b8aA
Description:	High Resolution Structure of the HDGF PWWP Domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [119-338]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDSLDATEPG LTKAEIVDGT DHIVIESERT DNFNFRVDPC FPKLDENNGE ERKAEIRKLD  60
   61 SSSFLESKVK TTSPVSESLE HSSFDPKIKK EDFDKGTDGS ACNEHFGNGQ KKLANGKRIK 120
  121 KEAGGSDRKG EDTVHRDKSN NSHVPGGRTA SGNSDSKKSK GLLTEKTSSK VSADKHENSP 180
  181 GIKVGVSGKK RRLESEQGKL APRVDESSRA AKKPRCESAD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [339-400]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKVKCEIDDG SDSTGTVSDI KREIVLGLGA RGGNFQYDKE AVAYTKRQRQ TMEHATSPSF  60
   61 SG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [401-559]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRDKSGKGHL EQKDRSSPVR NVKAPAAQSL KKRRAVCIYD EDDDEDPKTP LHGKPAIVPQ  60
   61 AASVLTDGPK RANVCHSTST KAKISAGSTE STEVRKFPLR KHCEDASRVL PSNAENSTNS 120
  121 LPVVKPINEL PPKDVKQILQ SPKMSPQLVL TNKHVAGQH

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [560-757]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVVKSSVKVS GVVMAKKPQS DSCKEAVAGS DKISSSQSQP ANQRHKSASV GERLTVVSKA  60
   61 ASRLNDSGSR DMSEDLSAAM LDLNREKGSA TFTSAKTPDS AASMKDLIAA AQAKRKLAHT 120
  121 QNSIFGNLNP SFLSISDTQG RSHSPFMVQN ASASAAISMP LVVQGHHQQG SSPSNHGHQS 180
  181 LSRNQIETDD NEERRLSS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6

Region A:
Residues: [758-953]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHKSVGGSLS CSTEAAISRD AFEGMLETLS RTRESIGRAT RLAIDCAKYG LASEVVELLI  60
   61 RKLESESHFH RKVDLFFLVD SITQHSHSQK GIAGASYVPT VQAALPRLLG AAAPPGTGAS 120
  121 DNRRKCLKVL KLWLERKVFP ESLLRRYIDD IRASGDDATG GFSLRRPSRS ERAVDDPIRE 180
  181 MEGMLVDEYG SNATFQ

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	3.443697
Match:	PF04818.5
Description:	No description for PF04818.5 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7

Region A:
Residues: [954-1130]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPGFFSSHNF EDDEEDDDLP TSQKEKSTSA GERVSALDDL EIHDTSSDKC HRVLEDVDHE  60
   61 LEMEDVSGQR KDVAPSSFCE NKTKEQSLDV MEPVAEKSTE FNPLPEDSPP LPQESPPPLP 120
  121 PLPPSPPPPS PPLPPSSLPP PPPAALFPPL PPPPSQPPPP PLSPPPSPPP PPPPPSQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #8

Region A:
Residues: [1131-1294]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLTTQLSIAS HHQIPFQPGF PPPTYPLSHQ TYPGSMQQDR SSIFTGDQIV QGPGNSSRGG  60
   61 LVEGAGKPEY FVQQSSSFSP AGVCSSREPS SFTSSRQLEF GNSDVLFNPE ASSQNHRFQP 120
  121 STPLSQRPMV RLPSAPSSHF SYPSHIQSQS QHSYTHPYPF PPQR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.522879
Match:	1m2vB
Description:	Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #9

Region A:
Residues: [1295-1392]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDARRYRNEE PWRIPSSGHS AENQNGAWIH GRNSHPGLPR VTDSFFRPPP ERPPSGTMNY  60
   61 QPSAASNLQA VPAIPGHTAP QMLPSRPDIP TVNCWRPA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.2	NCBI nr	03/2009
PSI-BLAST	2.2.22	FFAS	ffas03
PDB	10/2008	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits