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View Structure Prediction Details

Protein: FTSH4_ARATH
Organism: Arabidopsis thaliana
Length: 717 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FTSH4_ARATH.

Description E-value Query
Range
Subject
Range
gi|254238513, gi... - gi|84317370|ref|ZP_00965818.1| COG0465: ATP-dependent Zn proteases [Pseudomonas aeruginosa C3719], g...
gi|194555332, gi... - gi|84323594|ref|ZP_00971663.1| COG0465: ATP-dependent Zn proteases [Pseudomonas aeruginosa 2192], gi...
gi|218893846, gi... - gi|218893846|ref|YP_002442715.1| cell division protein FtsH [Pseudomonas aeruginosa LESB58], gi|2187...
gi|9951013, gi|1... - gi|9951013|gb|AAG08137.1|AE004888_12 cell division protein FtsH [Pseudomonas aeruginosa PAO1], gi|15...
gi|107103848 - gi|107103848|ref|ZP_01367766.1| hypothetical protein PaerPA_01004919 [Pseudomonas aeruginosa PACS2]
gi|11347548 - pir||F83053 cell division protein FtsH PA4751 [imported] - Pseudomonas aeruginosa (strain PAO1)
gi|53726399, gi|... - gi|53726399|ref|ZP_00141191.2| COG0465: ATP-dependent Zn proteases [Pseudomonas aeruginosa UCBPP-PA1...
gi|94417365 - gi|94417365|ref|ZP_01297183.1| hypothetical protein PaerP_01000682 [Pseudomonas aeruginosa PA7]
475.0 [0..188] [701..115]

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Predicted Domain #1
Region A:
Residues: [1-211]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAWRRIITKV SSHERELSSL RSLLVRAYSS FPRVGVTGAV GGGGASLPRT RFQSSYVGSF  60
   61 ARRVRDREEV NEVAHLRELI RRNDPEAVIR MFESQPSLHA NASALSEYIK ALVKVDRLDQ 120
  121 SELVRTLQRG IAGVAREEET FGGLGAFRNV GKPTKDGVLG TASAPIHTIS TERTHFKEQL 180
  181 WSTIRTIGVG FLLISGIGAL IEDRGIGKGL G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [212-474]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LHEEVQPSMD SSTKFSDVKG VDEAKAELEE IVHYLRDPKR FTRLGGKLPK GVLLVGPPGT  60
   61 GKTMLARAIA GEAGVPFFSC SGSEFEEMFV GVGARRVRDL FSAAKKCSPC IIFIDEIDAI 120
  121 GGSRNPKDQQ YMKMTLNQML VELDGFKQNE GIIVVAATNF PESLDKALVR PGRFDRHIVV 180
  181 PNPDVEGRRQ ILESHMSKVL KAEDVDLMII ARGTPGFSGA DLANLVNVAA LKAAMDGSKD 240
  241 VTMSDLEFAK DRIMMGSERK SAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 70.0
Match: 1lv7A
Description: AAA domain of cell division protein FtsH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.470983068319171 bayes_pls_golite062009
hydrolase activity 0.0582794297634999 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [475-529]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISDESRKLTA FHEGGHALVA IHTEGALPVH KATIVPRGMA LGMVSQLPDK DETSI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.09
Match: 2di4A
Description: No description for 2di4A was found.

Predicted Domain #4
Region A:
Residues: [530-717]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRKQMLARLD VCMGGRVAEE LIFGESEVTS GASSDLEQAT KLARAMVTKF GMSKEVGLVA  60
   61 HNYDDNGKSM STETRLLIES EVKQLLEKAY NNAKTILTVY NKELHALANA LLQHETLSGK 120
  121 QIKELLTDLN SPLLQKRQEV VTKQSNPVPP STPSSASSAA AAAAAAAAAA AAAAATAATK 180
  181 GKDMAPVS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 114.0
Match: 2ce7A
Description: EDTA treated
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle