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View Structure Prediction Details

Protein: ILV5_ARATH
Organism: Arabidopsis thaliana
Length: 591 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ILV5_ARATH.

Description E-value Query
Range
Subject
Range
ILV5_PEA - Ketol-acid reductoisomerase, chloroplastic OS=Pisum sativum GN=PGAAIR PE=2 SV=1
478.0 [0..1] [591..1]

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Predicted Domain #1
Region A:
Residues: [1-66]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAATSSIAP SLSCPSPSSS SKTLWSSKAR TLALPNIGFL SSSSKSLRSL TATVAGNGAT  60
   61 GSSLAA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.30103
Match: 1ygyA
Description: Crystal Structure of D-3-Phosphoglycerate dehydrogenase From Mycobacterium tuberculosis
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [67-591]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RMVSSSAVKA PVSLDFETSV FKKEKVSLAG YEEYIVRGGR DLFKHLPDAF KGIKQIGVIG  60
   61 WGSQGPAQAQ NLRDSLVEAK SDIVVKIGLR KGSRSFEEAR AAGFTEESGT LGDIWETIAG 120
  121 SDLVLLLISD AAQADNYEKI FSHMKPNSIL GLSHGFLLGH LQSSGLDFPK NISVVAVCPK 180
  181 GMGPSVRRLY VQGKEINGAG INASFAVHQD VDGRAADVAL GWSVALGSPF TFATTLEQEY 240
  241 RSDIFGERGI LLGAVHGIVE SLFRRYTENG MSEDLAYKNT VECITGTISR TISTQGMLAV 300
  301 YNSLSEEGKK DFETAYSASF YPCMEILYEC YEDVQSGSEI RSVVLAGRRF YEKEGLPAFP 360
  361 MGNIDQTRMW KVGERVRKSR PAGDLGPLYP FTAGVYVALM MAQIEILRKK GHSYSEIINE 420
  421 SVIESVDSLN PFMHARGVSF MVDNCSTTAR LGSRKWAPRF DYILTQQALV AVDSGAAINR 480
  481 DLISNFFSDP VHGAIEVCAQ LRPTVDISVP ADADFVRPEL RQSSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 118.0
Match: 1qmgA
Description: Class II ketol-acid reductoisomerase; Class II ketol-acid reductoisomerase (KARI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity 3.32932637997329 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 2.05128385305465 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.96484346513217 bayes_pls_golite062009
catalytic activity 1.83291384546132 bayes_pls_golite062009
3-hydroxyisobutyrate dehydrogenase activity 1.1058263903657 bayes_pls_golite062009
binding 0.952664119620178 bayes_pls_golite062009
pyrroline-5-carboxylate reductase activity 0.887690130310844 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors 0.715028113460127 bayes_pls_golite062009
protein binding 0.423314151944334 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle