YRC Public Data Repository - Protein Structure Prediction

Protein:	FTSH5_ARATH
Organism:	Arabidopsis thaliana
Length:	704 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FTSH5_ARATH.

Description	E-value	Query Range	Subject Range
gi\|205357195, gi... - gi\|205357195\|ref\|ZP_02345811.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|197248059, gi... - gi\|197248059\|ref\|YP_002148220.1\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ent... gi\|195873641, gi... - gi\|195873641\|ref\|ZP_02697399.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|194471603, gi... - gi\|194471603\|ref\|ZP_03077587.1\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|194447870, gi... - gi\|194447870\|ref\|YP_002047324.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ... gi\|194442507, gi... - gi\|194442507\|ref\|YP_002042552.1\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ent... gi\|205348591, gi... - gi\|205360607\|ref\|ZP_02684667.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|205343557, gi... - gi\|205359745\|ref\|ZP_02831638.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|205359196, gi... - gi\|205359196\|ref\|ZP_02668061.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|62181804, gi\|... - gi\|62181804\|ref\|YP_218221.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica sero... gi\|205333758, gi... - gi\|205358490\|ref\|ZP_02656962.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente...	632.0	[0..92]	[703..3]
FTSH_SALTI - Cell division protease ftsH OS=Salmonella typhi GN=hflB PE=3 SV=1 FTSH_SALTY - Cell division protease ftsH OS=Salmonella typhimurium GN=hflB PE=3 SV=1 gi\|214000933 - gi\|214000933\|ref\|ZP_03411668.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... gi\|224585091, gi... - gi\|224585091\|ref\|YP_002638890.1\| cell division protein [Salmonella enterica subsp. enterica serovar ... gi\|56129482, gi\|... - gi\|56415225\|ref\|YP_152300.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica sero... gi\|238910089 - gi\|238910089\|ref\|ZP_04653926.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... gi\|207858544, gi... - gi\|207858544\|ref\|YP_002245195.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ... gi\|213052988 - gi\|213052988\|ref\|ZP_03345866.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... lcl\|NC_016856.1_... - [gene=hflB] [protein=ATP-dependent metalloprotease] [protein_id=YP_005239474.1] [location=complement... gi\|213425426 - gi\|213425426\|ref\|ZP_03358176.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... gi\|213852786 - gi\|213852786\|ref\|ZP_03382318.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... gi\|29143547, gi\|... - gi\|29143547\|ref\|NP_806889.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica sero... gi\|160867488, gi... - gi\|161506141\|ref\|YP_001573253.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. arizonae ... FTSH_SALTY - ATP-dependent zinc metalloprotease FtsH OS=Salmonella typhimurium GN=ftsH PE=3 SV=1 gi\|16762058 - gi\|16762058\|ref\|NP_457675.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica sero... gi\|161616303, gi... - gi\|161616303\|ref\|YP_001590268.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ... FTSH_SALTI - ATP-dependent zinc metalloprotease FtsH OS=Salmonella typhi GN=ftsH PE=3 SV=1 gi\|197364155, gi... - gi\|197364155\|ref\|YP_002143792.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ... FTSH_SALTY - ATP-dependent zinc metalloprotease FtsH OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 7007... gi\|205273978, gi... - gi\|205354197\|ref\|YP_002227998.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ...	631.0	[0..93]	[703..1]
gi\|746401 - gi\|746401\|gb\|AAA97508.1\| ATP-binding protein gi\|188487047, gi... - gi\|188491848\|ref\|ZP_02999118.1\| ATP-dependent metallopeptidase HflB [Escherichia coli 53638], gi\|188... gi\|157068341, gi... - gi\|157162661\|ref\|YP_001459979.1\| ATP-dependent metalloprotease [Escherichia coli HS], gi\|157068341\|g... gi\|157080734, gi... - gi\|157158704\|ref\|YP_001464653.1\| ATP-dependent metalloprotease [Escherichia coli E24377A], gi\|157080... gi\|226839967, gi... - gi\|254038343\|ref\|ZP_04872401.1\| ATP-dependent metalloprotease [Escherichia sp. 1_1_43], gi\|226839967... gi\|253771988, gi... - gi\|253771988\|ref\|YP_003034819.1\| ATP-dependent metalloprotease FtsH [Escherichia coli BL21(DE3)], gi... gi\|237706070, gi... - gi\|237706070\|ref\|ZP_04536551.1\| ATP-dependent metalloprotease [Escherichia sp. 3_2_53FAA], gi\|226899... gi\|194411725, gi... - gi\|194430224\|ref\|ZP_03062722.1\| ATP-dependent metallopeptidase HflB [Escherichia coli B171], gi\|1944... tr\|A0A0G3HSQ2\|A0... - ATP-dependent zinc metalloprotease FtsH OS=Escherichia coli (strain K12) GN=ftsH PE=3 SV=1 gi\|191168060, gi... - gi\|191168060\|ref\|ZP_03029860.1\| ATP-dependent metallopeptidase HflB [Escherichia coli B7A], gi\|19090...	631.0	[0..92]	[703..3]
gi\|76884341, gi\|... - gi\|77166027\|ref\|YP_344552.1\| peptidase M41, FtsH [Nitrosococcus oceani ATCC 19707], gi\|76884341\|gb\|A...	630.0	[0..92]	[703..3]
gi\|75240799 - gi\|75240799\|ref\|ZP_00724697.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli F11]	630.0	[0..93]	[703..1]
gi\|218555748, gi... - gi\|218555748\|ref\|YP_002388661.1\| ATP-dependent metalloprotease [Escherichia coli IAI1], gi\|218362516... gi\|218358002, gi... - gi\|218550461\|ref\|YP_002384252.1\| ATP-dependent metalloprotease [Escherichia fergusonii ATCC 35469], ... gi\|218429032, gi... - gi\|218691468\|ref\|YP_002399680.1\| ATP-dependent metalloprotease [Escherichia coli ED1a], gi\|218429032... gi\|218367017, gi... - gi\|218560248\|ref\|YP_002393161.1\| ATP-dependent metalloprotease [Escherichia coli S88], gi\|218367017\|... gi\|218701947, gi... - gi\|218701947\|ref\|YP_002409576.1\| ATP-dependent metalloprotease [Escherichia coli IAI39], gi\|21837193... gi\|218696883, gi... - gi\|218696883\|ref\|YP_002404550.1\| ATP-dependent metalloprotease [Escherichia coli 55989], gi\|21835361... gi\|218706798, gi... - gi\|218706798\|ref\|YP_002414317.1\| ATP-dependent metalloprotease [Escherichia coli UMN026], gi\|2184338... FTSH_ECOLI - Cell division protease ftsH (EC 3.4.24.-) - Escherichia coli EG11506 - protease, ATP-dependent zinc-metallo / ATP-dependent membrane protease, complexed with HflCK; regula... FTSH_SHIFL - ATP-dependent zinc metalloprotease FtsH OS=Shigella flexneri GN=ftsH PE=3 SV=1 gi\|24053649, gi\|... - gi\|24114467\|ref\|NP_708977.1\| ATP-dependent metalloprotease [Shigella flexneri 2a str. 301], gi\|24053... gi\|30042775, gi\|... - gi\|30064516\|ref\|NP_838687.1\| ATP-dependent metalloprotease [Shigella flexneri 2a str. 2457T], gi\|300... EG11506 - protease, ATP-dependent zinc-metallo / ATP-dependent membrane protease, complexed with HflCK; regula... gi\|227887899, gi... - gi\|227887899\|ref\|ZP_04005704.1\| M41 family endopeptidase FtsH [Escherichia coli 83972], gi\|227835295... gi\|238863291, gi... - gi\|238902280\|ref\|YP_002928076.1\| protease, ATP-dependent zinc-metallo [Escherichia coli BW2952], gi\|... gi\|251786448, gi... - gi\|251786448\|ref\|YP_003000752.1\| hypothetical protein B21_02994 [Escherichia coli BL21], gi\|24237872... gi\|253975021, gi... - gi\|254163120\|ref\|YP_003046228.1\| protease, ATP-dependent zinc-metallo [Escherichia coli B str. REL60... gi\|253979177, gi... - gi\|254289870\|ref\|YP_003055618.1\| protease, ATP-dependent zinc-metallo [Escherichia coli BL21(DE3)], ... gi\|169890548, gi... - gi\|170082713\|ref\|YP_001732033.1\| subunit of integral membrane ATP-dependent zinc metallopeptidase [E... gi\|169753500, gi... - gi\|170018572\|ref\|YP_001723526.1\| ATP-dependent metalloprotease [Escherichia coli ATCC 8739], gi\|1697... gi\|215266566, gi... - gi\|215488494\|ref\|YP_002330925.1\| ATP-dependent metalloprotease [Escherichia coli O127:H6 str. E2348/... gi\|209920653, gi... - gi\|209920653\|ref\|YP_002294737.1\| ATP-dependent metalloprotease [Escherichia coli SE11], gi\|209913912... gi\|75197127 - gi\|75197127\|ref\|ZP_00707197.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli HS] gi\|75208502 - gi\|75208502\|ref\|ZP_00708822.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli B171] gi\|75187984 - gi\|75187984\|ref\|ZP_00701251.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli E24377A] gi\|146028, gi\|89... - gi\|89109941\|ref\|AP_003721.1\| protease, ATP-dependent zinc-metallo [Escherichia coli str. K-12 substr... gi\|91074173, gi\|... - gi\|91212599\|ref\|YP_542585.1\| ATP-dependent metalloprotease [Escherichia coli UTI89], gi\|91074173\|gb\|... gi\|117625472, gi... - gi\|117625472\|ref\|YP_858795.1\| ATP-dependent metalloprotease [Escherichia coli APEC O1], gi\|115514596... gi\|110345010, gi... - gi\|110643418\|ref\|YP_671148.1\| ATP-dependent metalloprotease [Escherichia coli 536], gi\|110345010\|gb\|... gi\|75228765 - gi\|75228765\|ref\|ZP_00715374.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli B7A] gi\|110616592, gi... - gi\|110807044\|ref\|YP_690564.1\| ATP-dependent metalloprotease [Shigella flexneri 5 str. 8401], gi\|1106... gi\|74313715, gi\|... - gi\|74313715\|ref\|YP_312134.1\| ATP-dependent metalloprotease [Shigella sonnei Ss046], gi\|73857192\|gb\|A...	630.0	[0..93]	[703..1]
gi\|37528354, gi\|... - gi\|37528354\|ref\|NP_931699.1\| ATP-dependent metalloprotease [Photorhabdus luminescens subsp. laumondi...	630.0	[0..92]	[703..3]
FTSH_ECO57 - ATP-dependent zinc metalloprotease FtsH OS=Escherichia coli O157:H7 GN=ftsH PE=3 SV=1 gi\|13363530, gi\|... - gi\|15833311\|ref\|NP_312084.1\| ATP-dependent metalloprotease [Escherichia coli O157:H7 str. Sakai], gi... gi\|254594527, gi... - gi\|254795127\|ref\|YP_003079964.1\| subunit of integral membrane ATP-dependent zinc metallopeptidase [E... gi\|209758260, gi... - pir\|\|D85981 cell division protein HflB/FtsH proteinase [imported] - Escherichia coli (strain O157:H7... gi\|209160879, gi... - gi\|209399479\|ref\|YP_002272648.1\| ATP-dependent metallopeptidase HflB [Escherichia coli O157:H7 str. ... gi\|195938397 - gi\|195938397\|ref\|ZP_03083779.1\| ATP-dependent metalloprotease [Escherichia coli O157:H7 str. EC4024] gi\|15803718, gi\|... - gi\|15803718\|ref\|NP_289752.1\| ATP-dependent metalloprotease [Escherichia coli O157:H7 EDL933], gi\|125... gi\|217319989, gi... - gi\|217327622\|ref\|ZP_03443705.1\| ATP-dependent metallopeptidase HflB [Escherichia coli O157:H7 str. T...	630.0	[0..93]	[703..1]
gi\|53757631, gi\|... - gi\|53803870\|ref\|YP_114285.1\| cell division protein FtsH [Methylococcus capsulatus str. Bath], gi\|537...	630.0	[0..91]	[704..2]
gi\|82778492, gi\|... - gi\|82778492\|ref\|YP_404841.1\| ATP-dependent metalloprotease [Shigella dysenteriae Sd197], gi\|81242640...	629.0	[0..93]	[703..1]

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Predicted Domain #1

Region A:
Residues: [1-90]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATTSSNPLL LSSNFLGSQI IISAPTPKTT TKSLPFSVIS RKRYQISQSE KLMKSLPSQA  60
   61 ALAALLFSSS SPQALAVNEP VQPPAPTITA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [91-234]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAQSPNLSTF GQNVLMTAPN PQAQSSDLPD GTQWRYSEFL NAVKKGKVER VKFSKDGSVL  60
   61 QLTAVDNRRA TVIVPNDPDL IDILAMNGVD ISVSEGEGGN GLFDFIGNLL FPLLAFGGLF 120
  121 YLFRGGQGGA GGPGGLGGPM DFGR

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	19.568636
Match:	PF06480.6
Description:	No description for PF06480.6 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.822	N/A	N/A	c.20.1	Initiation factor IF2/eIF5b, domain 3

Predicted Domain #3

Region A:
Residues: [235-704]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKSKFQEVPE TGVTFGDVAG ADQAKLELQE VVDFLKNPDK YTALGAKIPK GCLLVGPPGT  60
   61 GKTLLARAVA GEAGVPFFSC AASEFVELFV GVGASRVRDL FEKAKSKAPC IVFIDEIDAV 120
  121 GRQRGAGMGG GNDEREQTIN QLLTEMDGFS GNSGVIVLAA TNRPDVLDSA LLRPGRFDRQ 180
  181 VTVDRPDVAG RVQILKVHSR GKAIGKDVDY EKVARRTPGF TGADLQNLMN EAAILAARRE 240
  241 LKEISKDEIS DALERIIAGP EKKNAVVSEE KKRLVAYHEA GHALVGALMP EYDPVAKISI 300
  301 IPRGQAGGLT FFAPSEERLE SGLYSRSYLE NQMAVALGGR VAEEVIFGDE NVTTGASNDF 360
  361 MQVSRVARQM VERFGFSKKI GQVAVGGAGG NPFLGQSMSS QKDYSMATAD VVDAEVRELV 420
  421 EKAYVRAKEI ITTQIDILHK LAQLLIEKET VDGEEFMSLF IDGQAELYVS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	132.0
Match:	2ce7A
Description:	EDTA treated
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits