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View Structure Prediction Details

Protein: CNGC1_ARATH
Organism: Arabidopsis thaliana
Length: 716 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CNGC1_ARATH.

Description E-value Query
Range
Subject
Range
gi|6969231 - gi|6969231|gb|AAF33670.1|AF079872_1 cyclic nucleotide-gated calmodulin-binding ion channel [Nicotian...
366.0 [0..1] [716..1]
CNGC5_ARATH - Probable cyclic nucleotide-gated ion channel 5 OS=Arabidopsis thaliana GN=CNGC5 PE=2 SV=1
350.0 [0..1] [715..1]
gi|92895780, gi|... - gi|92895780|gb|ABE92841.1| Cyclic nucleotide-binding [Medicago truncatula], gi|92887211|gb|ABE88729....
332.0 [0..1] [716..12]
gi|7489415 - pir||T04424 probable calmodulin binding transport protein - barley
gi|3169012 - gi|3169012|emb|CAA05637.1| putative calmodulin binding transporter protein [Hordeum vulgare subsp. v...
327.0 [0..4] [716..3]

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Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFRQEKFVR FQDWKSDKTS SDVEYSGKNE IQTGIFQRTI SSISDKFYRS FESSSARIKL  60
   61 FKRSYKSYSF KEAVSKGIGS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.864 d.52.9 Description not found.
View Download 0.757 d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.757 d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.688 d.52.8 Description not found.
View Download 0.664 d.52.9 Description not found.
View Download 0.544 d.266.1 Description not found.
View Download 0.529 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.517 a.2.3 Chaperone J-domain
View Download 0.484 d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.462 a.36.1 Signal peptide-binding domain
View Download 0.374 a.231.1 Description not found.
View Download 0.358 d.58.4 Dimeric alpha+beta barrel
View Download 0.350 a.7.8 GAT domain
View Download 0.338 d.253.1 Description not found.

Predicted Domain #2
Region A:
Residues: [81-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 THKILDPQGP FLQRWNKIFV LACIIAVSLD PLFFYVPIID DAKKCLGIDK KMEITASVLR  60
   61 SFTDVFYVLH IIFQFRTGFI APSSRVFGRG VLVEDKREIA KRYLSSHFII DILAVLPLPQ 120
  121 MVILIIIP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.53
Match: 2a0lA
Description: Crystal structure of KvAP-33H1 Fv complex
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [209-416]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HMRGSSSLNT KNMLKFIVFF QYIPRFIRIY PLYKEVTRTS GILTETAWAG AAFNLFLYML  60
   61 ASHVFGAFWY LFSIERETVC WKQACERNNP PCISKLLYCD PETAGGNAFL NESCPIQTPN 120
  121 TTLFDFGIFL DALQSGVVES QDFPQKFFYC FWWGLQNLSS LGQNLKTSTY IWEICFAVFI 180
  181 SIAGLVLFSF LIGNMQTYLQ STTTRLEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.30103
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [417-489]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVKRRDAEQ WMSHRLLPEN LRKRIRRYEQ YKWQETRGVD EENLLSNLPK DLRRDIKRHL  60
   61 CLALLMRVPM FEK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.68
Match: 2ptmA
Description: No description for 2ptmA was found.

Predicted Domain #5
Region A:
Residues: [490-622]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEQLLDALC DRLQPVLYTE ESYIVREGDP VDEMLFIMRG KLLTITTNGG RTGFLNSEYL  60
   61 GAGDFCGEEL LTWALDPHSS SNLPISTRTV RALMEVEAFA LKADDLKFVA SQFRRLHSKQ 120
  121 LRHTFRYYSQ QWK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.045757
Match: 1wgpA
Description: Solution structure of the cNMP-binding domain from Arabidopsis thaliana cyclic nucleotide-regulated ion channel
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [623-716]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TWAACFIQAA WRRYIKKKLE ESLKEEENRL QDALAKEACG SSPSLGATIY ASRFAANILR  60
   61 TIRRSGSVRK PRMPERMPPM LLQKPAEPDF NSDD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.630 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.630 N/A N/A a.47.2 t-snare proteins
View Download 0.630 N/A N/A a.47.2 t-snare proteins
View Download 0.626 N/A N/A a.7.1 Spectrin repeat
View Download 0.619 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.597 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.597 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.591 N/A N/A a.7.1 Spectrin repeat
View Download 0.586 N/A N/A a.47.2 t-snare proteins
View Download 0.528 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits


YRC Informatics Platform - Version 3.0
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