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View Structure Prediction Details

Protein: CAS1_ARATH
Organism: Arabidopsis thaliana
Length: 759 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAS1_ARATH.

Description E-value Query
Range
Subject
Range
CAS1_GLYGL - Cycloartenol synthase OS=Glycyrrhiza glabra GN=GgCAS1 PE=1 SV=1
1035.0 [0..1] [757..1]

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Predicted Domain #1
Region A:
Residues: [1-759]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWKLKIAEGG SPWLRTTNNH VGRQFWEFDP NLGTPEDLAA VEEARKSFSD NRFVQKHSAD  60
   61 LLMRLQFSRE NLISPVLPQV KIEDTDDVTE EMVETTLKRG LDFYSTIQAH DGHWPGDYGG 120
  121 PMFLLPGLII TLSITGALNT VLSEQHKQEM RRYLYNHQNE DGGWGLHIEG PSTMFGSVLN 180
  181 YVTLRLLGEG PNDGDGDMEK GRDWILNHGG ATNITSWGKM WLSVLGAFEW SGNNPLPPEI 240
  241 WLLPYFLPIH PGRMWCHCRM VYLPMSYLYG KRFVGPITST VLSLRKELFT VPYHEVNWNE 300
  301 ARNLCAKEDL YYPHPLVQDI LWASLHKIVE PVLMRWPGAN LREKAIRTAI EHIHYEDENT 360
  361 RYICIGPVNK VLNMLCCWVE DPNSEAFKLH LPRIHDFLWL AEDGMKMQGY NGSQLWDTGF 420
  421 AIQAILATNL VEEYGPVLEK AHSFVKNSQV LEDCPGDLNY WYRHISKGAW PFSTADHGWP 480
  481 ISDCTAEGLK AALLLSKVPK AIVGEPIDAK RLYEAVNVII SLQNADGGLA TYELTRSYPW 540
  541 LELINPAETF GDIVIDYPYV ECTSAAIQAL ISFRKLYPGH RKKEVDECIE KAVKFIESIQ 600
  601 AADGSWYGSW AVCFTYGTWF GVKGLVAVGK TLKNSPHVAK ACEFLLSKQQ PSGGWGESYL 660
  661 SCQDKVYSNL DGNRSHVVNT AWAMLALIGA GQAEVDRKPL HRAARYLINA QMENGDFPQQ 720
  721 EIMGVFNRNC MITYAAYRNI FPIWALGEYR CQVLLQQGE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1w6kA
Description: Structure of human OSC in complex with Lanosterol
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
lanosterol synthase activity 3.72954210081462 bayes_pls_golite062009
oxidosqualene cyclase activity 3.70516211286781 bayes_pls_golite062009
prenyltransferase activity 3.525366989371 bayes_pls_golite062009
isoprenoid binding 1.59014951619756 bayes_pls_golite062009
binding 0.663474225223042 bayes_pls_golite062009
protein prenyltransferase activity 0.55742738134604 bayes_pls_golite062009
catalytic activity 0.497699107100544 bayes_pls_golite062009
protein binding 0.172880799019885 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle