YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC23C11.05
Organism:	Schizosaccharomyces pombe
Length:	289 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC23C11.05.

Description	E-value	Query Range	Subject Range
IPYR_DEBHA - Inorganic pyrophosphatase OS=Debaryomyces hansenii GN=IPP1 PE=3 SV=1 IPYR_DEBHA - Inorganic pyrophosphatase OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 00...	387.0	[0..3]	[287..2]
IPYR_PICPA - Inorganic pyrophosphatase OS=Komagataella pastoris GN=IPP1 PE=3 SV=3	382.0	[0..3]	[287..2]
IPYR_YARLI - Inorganic pyrophosphatase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=IPP1 PE=3 SV=1 IPYR_YARLI - Inorganic pyrophosphatase OS=Yarrowia lipolytica GN=IPP1 PE=3 SV=1	378.0	[0..1]	[287..1]
gi\|66852413, gi\|... - gi\|71000118\|ref\|XP_754776.1\| inorganic diphosphatase [Aspergillus fumigatus Af293], gi\|66852413\|gb\|E... gi\|159127784 - gi\|159127784\|gb\|EDP52899.1\| inorganic diphosphatase, putative [Aspergillus fumigatus A1163]	377.0	[0..3]	[287..110]
gi\|109089533 - gi\|109089533\|ref\|XP_001107614.1\| PREDICTED: similar to pyrophosphatase 1 [Macaca mulatta]	377.0	[0..1]	[283..200]
gi\|190408817 - gi\|190408817\|gb\|EDV12082.1\| inorganic pyrophosphatase [Saccharomyces cerevisiae RM11-1a] gi\|207347796 - gi\|207347796\|gb\|EDZ73861.1\| YBR011Cp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|151946405 - gi\|151946405\|gb\|EDN64627.1\| inorganic pyrophosphatase [Saccharomyces cerevisiae YJM789] IPP1 - Cytoplasmic inorganic pyrophosphatase (PPase), homodimer that catalyzes the rapid exchange of oxygen... IPYR_YEAST - Inorganic pyrophosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IPP1 PE=1 SV=4	376.0	[0..4]	[287..3]
IPYR_ASHGO - Inorganic pyrophosphatase OS=Ashbya gossypii GN=IPP1 PE=3 SV=1 IPYR_ASHGO - Inorganic pyrophosphatase OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-10...	376.0	[0..3]	[287..2]
gi\|145020555, gi... - gi\|39951911\|ref\|XP_363672.1\| inorganic pyrophosphatase [Magnaporthe grisea 70-15], gb\|EAA55947.1\| hy...	375.0	[0..2]	[287..3]
gi\|49091288, gi\|... - gi\|67525021\|ref\|XP_660572.1\| hypothetical protein AN2968.2 [Aspergillus nidulans FGSC A4], ref\|XP_40... IPYR_EMENI - Inorganic pyrophosphatase OS=Emericella nidulans GN=ipp1 PE=1 SV=1	375.0	[0..3]	[287..2]

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Predicted Domain #1

Region A:
Residues: [1-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEYTTREVG ALNTLDYQVY VEKNGTPISS WHDIPLYANA EKTILNMVVE IPRWTQAKLE  60
   61 ITKEATLNPI KQDTKKGKLR FVRNCFPHHG YIWNYGAFPQ TYEDPNVVHP ETKAKGDSDP 120
  121 LDVCEIGEAR GYTGQVKQVK VLGVMALLDE GETDWKVIVI DVNDPLAPKL NDIEDVERHM 180
  181 PGLIRATNEW FRIYKIPDGK PENSFAFSGE CKNRKYAEEV VRECNEAWER LITGKTDAKS 240
  241 DFSLVNVSVT GSVANDPSVS STIPPAQELA PAPVDPSVHK WFYISGSPL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	105.0
Match:	1m38A
Description:	Inorganic pyrophosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
inorganic diphosphatase activity	2.74116819406619	bayes_pls_golite062009
binding	1.77492613217844	bayes_pls_golite062009
catalytic activity	1.33262120571864	bayes_pls_golite062009
hydrolase activity	0.715768350203578	bayes_pls_golite062009
protein binding	0.38607803003281	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: