YRC Public Data Repository - Protein Structure Prediction

Protein:	tht1
Organism:	Schizosaccharomyces pombe
Length:	543 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tht1.

Description	E-value	Query Range	Subject Range
gi\|2506923, gi\|1... - gi\|2506923\|sp\|Q09684.2\|KAR5_SCHPO RecName: Full=Nuclear fusion protein tht1; AltName: Full=Twin hors... KAR5_SCHPO - Nuclear fusion protein tht1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=tht1 PE=1 SV=2	398.0	[0..1]	[543..35]
gi\|68388302 - gi\|68388302\|ref\|XP_696268.1\| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]	167.0	[0..2]	[383..1875]
gi\|3668187 - gi\|3668187\|dbj\|BAA33452.1\| myosin heavy chain [Theragra chalcogramma]	141.0	[0..2]	[384..873]
gi\|50757613 - gi\|50757613\|ref\|XP_415578.1\| PREDICTED: similar to myosin heavy chain [Gallus gallus]	126.0	[0..2]	[384..822]
gi\|73955710 - gi\|73955710\|ref\|XP_850299.1\| PREDICTED: similar to myosin, heavy polypeptide 13, skeletal muscle iso...	123.0	[0..2]	[384..875]
gi\|76643939 - gi\|76643939\|ref\|XP_872424.1\| PREDICTED: similar to myosin, heavy polypeptide 4, skeletal muscle, par...	117.0	[0..2]	[391..696]
gi\|58377263, gi\|... - gi\|58377263\|ref\|XP_309510.2\| ENSANGP00000012681 [Anopheles gambiae str. PEST], gi\|55244853\|gb\|EAA052...	115.0	[0..1]	[403..1356]
gi\|47205359 - gi\|47205359\|emb\|CAF96150.1\| unnamed protein product [Tetraodon nigroviridis]	115.0	[0..6]	[384..787]
gi\|70870905 - gi\|70870905\|gb\|EAN85153.1\| hypothetical protein, conserved [Trypanosoma cruzi] gi\|71409302 - gi\|71409302\|ref\|XP_807004.1\| hypothetical protein [Trypanosoma cruzi strain CL Brener]	113.0	[0..1]	[396..615]

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Predicted Domain #1

Region A:
Residues: [1-319]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYSNVAFSE GLAGFDSLAH VYQALLKKST CYQEVAATLI SKCSLLNTEL TIDNRIHSAI  60
   61 QMTLCDFERS QILAPSECVR GSQSECVSKL ESTSTWWLSF TSHFHDVNHL CRLANLEMQK 120
  121 ELSIEVNMNV TLVQKQFLEM VILHLRNFES VTDKMNQRID KFDGKFNSVI ENSFKDINFR 180
  181 VNQEIMGLVE LQNHQQEGMV QQKEILSTIK QLKSEIFDIN SFFANFIEES AGYSNSLIEK 240
  241 LNEKFTSENA IALSAIGKYT SEFSAFMEKR IKNLITTTED SLQQSVQSNI DFVNSGFQPL 300
  301 YDLTIQLKEE LQSLKRLSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.39794
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [320-398]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQQNLQHEQI LQWKSDFLNV SKDHLKVLQQ LRPLIDIVEK FMNVYFKGLS NIISSFAFIG  60
   61 FTLFATLSSL FFKVLKIHR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.69897
Match:	2iw5A
Description:	No description for 2iw5A was found.

Predicted Domain #3

Region A:
Residues: [399-543]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPIIVFGSLS IIFIHIYCFK ITSWVNLYGW ITCTIARTLS FIKLNIRTFY LTAFLCALLN  60
   61 FLRYLKYRNS KKDTELSLFL PAPEECNIYH NEHIQVQEDN YLCPIENSLI DLFGSENNKE 120
  121 KLGKQENVRF AFLNSESLEQ SPWWD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits