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View Structure Prediction Details

Protein: CE36160
Organism: Caenorhabditis elegans
Length: 646 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE36160.

Description E-value Query
Range
Subject
Range
gi|49900979 - gi|49900979|gb|AAH75862.1| CAPN1 protein [Homo sapiens]
585.0 [0..12] [628..1]

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Predicted Domain #1
Region A:
Residues: [1-646]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSPQEEELL ELIEKYNEDK YCTNMNWTIF LGDHENEKEA NEKFKSILED CQRSKSAFID  60
   61 KEFPHEPKSY MTFDEQSKVY GKYESWKTWL FPKIWRRITP PSTDVSSSLS VYNPLTFTAY 120
  121 EVFQRKVGDC GLVAALSAIS TKPEVIMNIF DSLQLSKYGV YKVKLFVDGQ WKTIIIDDYF 180
  181 PYTTDGIRIG ATSGYQIWAA LIEKALVKEC GNYKGIHGFQ SLSAFSALTG SPVLLIPVAK 240
  241 MFNNLRKYWK TLMEFRNNQY PMACGTLNRE VNGILPQHAY TIMDIVERDG HKLLLLRNPS 300
  301 GGSVWTRNWS KEWEWWPENM KDLLEGMIRG SFWISWDDFL NVFCSIYVCR HRSNWFAYYA 360
  361 KLVLKYPEDD AFPAIDIKVT EKCMVCISAV DDWISREVLL KTVEFQMPKY VQRYSWIAVH 420
  421 KINGIFSDNK KVVACEIIND STQDIDLEPG IYTITVIYLN DWSLDKRDIS IHSSRPISVN 480
  481 EGFSRTRKDS VHIKYIVDKF GQEIVKEQKD KMSIKKYTDN NFTFIAVVAW NFTYDQFLHA 540
  541 HLRYSITDEQ FVSRSLEDKQ TVDVIPPRRH QVLVVINLEA MPEIVDFPID IDYKLSKDVD 600
  601 ATINGIKRGC HLPEISSSRF LEYVHREEII SLDDFIPEIE VLSKLN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 164.0
Match: 1kfuL
Description: Calpain large subunit, C-terminal domain (domain IV); Calpain large subunit, middle domain (domain III); Calpain large subunit, catalytic domain (domain II)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.529663942126259 bayes_pls_golite062009
hydrolase activity 0.16837900182603 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle