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View Structure Prediction Details

Protein: unc-75
Organism: Caenorhabditis elegans
Length: 514 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-75.

Description E-value Query
Range
Subject
Range
gi|73981466 - gi|73981466|ref|XP_850830.1| PREDICTED: similar to trinucleotide repeat containing 4 isoform 2 [Cani...
305.0 [0..23] [514..1]

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Predicted Domain #1
Region A:
Residues: [1-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQQQHEMRA SSTSSTDSNG FPVKDPDAIK LFVGQIPRNL EEKDLRHLFE QFGKIYEFTI  60
   61 LKDKYTGMHK GCAFLTYCHR DSAVRCQATL HDQKTLPGMN RAMQVKPADT DSRPASPKDK 120
  121 MDDKKLFIGM LSKQQSEDEV RALFATFGEL DEVTVLRGAD GASKGCAFVK YKHGLDAHMA 180
  181 ISALHGSQTM PGASSSLVVK YADTEKERQN RRMQQMAAQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.221849
Match: 2dhsA
Description: No description for 2dhsA was found.

Predicted Domain #2
Region A:
Residues: [220-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGMLNPMLVN QVGMQYNAYQ QVLQQQSLAA QTNAMASAAY LPLLQQQTTD PLHVLQLQAA  60
   61 AAAAQAAANP VLSQQTQQQQ QQQQQLAAQL QLQSAAAQNP HYALAAQALA QQQAAQQAQA 120
  121 VVAHSHAQVH QHQTAQVTST ASHAQTENPA ASSYGSLAAA AAAANYSSLL SGMESQHNAA 180
  181 AALQLAQIQQ QAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [413-514]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AALPMVTPRE VLGPDGCNLF IYHLPQEFGD AELIQMFAPF GHIVSAKVFV DRATNQSKCF  60
   61 GFVSYDNIHS SQAAITAMNG FQIGMKRLKV QLKRPRNESR PY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.221849
Match: 2cpzA
Description: solution structure of RNA binding domain 3 in CUG triplet repeat RNA-binding protein 1
Matching Structure (courtesy of the PDB):

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