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View Structure Prediction Details

Protein: CE35845
Organism: Caenorhabditis elegans
Length: 393 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE35845.

Description E-value Query
Range
Subject
Range
PUR9_ALTMD - Bifunctional purine biosynthesis protein PurH OS=Alteromonas macleodii (strain DSM 17117 / Deep ecot...
PUR9_ALTMD - Bifunctional purine biosynthesis protein PurH OS=Alteromonas mediterranea (strain DSM 17117 / CIP 11...
524.0 [0..2] [393..132]

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Predicted Domain #1
Region A:
Residues: [1-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRISSMAYK WKQPPPPIND DSRHRSQSNS RLFDRIYGQM HRGNKAFEHT TSYDESISGF  60
   61 MRRRFAGNGE RALPLRYGTN PHQKDDAELY IVEDEMPIKV LNGSPGYINI LDGLNGWQLV 120
  121 KELSDATKMP AAASFKHVSP AGAAVGLPLN ETEAACCMVS DLPIDTKKPS LAAAYARARG 180
  181 ADRMSSFGDF IALSEKCDEL TAKIINREVS DGVVAPDFDP AALSLLAKKK NGNYCVLKIN 240
  241 PNYLPSETEE RTVFGLRLRQ KRNNAVINAE TFNNVVGSAN ELNKQAIDDL IVATIALKYA 300
  301 QSNSVCFAHR GQVIGMGAGQ QSRIHCTRLA GDKAMNWWLR QHPTVLSLPW KNAIKRSEKS 360
  361 NAIDVLCSGV LGSEVCNFKF NRPLSYFSLV TNL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 138.0
Match: 1p4rA
Description: Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.177505784657 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle