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View Structure Prediction Details

Protein: CE35555
Organism: Caenorhabditis elegans
Length: 315 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE35555.

Description E-value Query
Range
Subject
Range
gi|47208951 - gi|47208951|emb|CAF92242.1| unnamed protein product [Tetraodon nigroviridis]
174.0 [0..23] [314..50]

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Predicted Domain #1
Region A:
Residues: [1-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSLISLKSI RPFNRDFLFS NTLHIRRTLK ELLEVTHKPM LDMVNMDLPT NGVVADERKF  60
   61 EAYIYKLNDR LTQCGMHSRI PPNSSDVTSG GPCPRNLAIS LGHIAYRFAI PDANELRHYA 120
  121 AGSSTIYGEI NLEQMASFVD ELNIGPNDHF MDLGSGVGQL VSFVAAYAQT KKSVGVEIMP 180
  181 NLAQMARANE QFSKSLLRHF GKTVNPTRLV HGSFTSPDIV HEIQNEATVI CVNNIKFSAE 240
  241 LKLELKMILS KCADGTRIIS SESIAPRPRS QNSTSSRVDE FVRISTERPL LLVESNTSWT 300
  301 GNTVPFYLTE IKHNQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.522879
Match: 1nw3A
Description: Catalytic, N-terminal domain of histone methyltransferase Dot1l
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.723277178398499 bayes_pls_golite062009
transferase activity 0.64512166557639 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.54403439349476 bayes_pls_golite062009
methyltransferase activity 0.54389223881989 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle