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View Structure Prediction Details

Protein: lgc-43
Organism: Caenorhabditis elegans
Length: 679 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lgc-43.

Description E-value Query
Range
Subject
Range
gi|39581842, gi|... - gi|39581842|emb|CAE60735.1| Hypothetical protein CBG04419 [Caenorhabditis briggsae], gi|187035783|em...
gi|157758305 - gi|157758305|ref|XP_001671496.1| Hypothetical protein CBG04419 [Caenorhabditis briggsae AF16]
586.0 [0..1] [658..1]

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Predicted Domain #1
Region A:
Residues: [1-141]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMIRCSLSII CILLSLSVIR IDANEVLTTE ASTDSSSPTS SIFDWIPFKL FGSEKTTPIL  60
   61 RIKVRAVNRV IYTKKDNLLQ EIENASEYKK EQEKQFEQIP DVSTEVKEVS INEPDKMYER 120
  121 GEEPKIFLFP KQGNTVPKIE G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [142-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EFEKVDIIGE VSEDKVKTPK DDDFQIMYDD ELKEYVLKRR PLKMDKNGII DSWNGGDTKE  60
   61 IMDDSDDEVK RILE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [216-312]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGEEGLVGKN NRTLKTQQRN HTEVTLEEEE INLEDLQFKS YQFKPGKSKI RTYDLAWMDP  60
   61 SFLEKEEFSV RLTSQQRSDW RDKLTNLTML EERRANE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [313-679]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HRDYGSSYIL PVLKSVDYDN TSVPLAFNDI PVNVAVAFNF LYLANFDSEM MEFSMDVEME  60
   61 FSWIDIRLVN NYTKPIRIRE KPIIEQIWRP DPYIVNSKHS YFHYVSFPNI RMRITPEGLV 120
  121 TYTVRVSSVC SCFMSFCLYP HDRQECDLRI SSIAYSNQYV KFHWHSNPIK FQSKITLPEL 180
  181 HITKIKTAEC STKGKLVDAS CLRIIFSLER DSARFVIEKY VPSTLAMMFA WVAPYVPYNY 240
  241 EDVRIITPIT VLLTLVQMEK GDKEIRTSYL TSIDVWFAAM KSFTVLSLLE SLAVLALIKR 300
  301 SRAMTKNAER AANEFERCTF EAEAYRLNRL YHRVDSICRF SSPVVFVAFF VYYVLFVAQG 360
  361 NENCVQI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 73.522879
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle