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View Structure Prediction Details

Protein: dlg-1
Organism: Caenorhabditis elegans
Length: 392 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dlg-1.

Description E-value Query
Range
Subject
Range
gi|7496493 - gi|7496493|pir||T15617 hypothetical protein C25F6.2 - Caenorhabditis elegans
270.0 [0..1] [391..144]

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Predicted Domain #1
Region A:
Residues: [1-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSLLDIHDL YEQTLLSERK SDAEKNMEVR RVIERLEGGP HSYNSRPAAT TSTSNYNLSS  60
   61 TTPLISDLRD RGGFSYLNGG GLGNGLGNGL GNGLLSSPYN SSSTHYLHER QRQTSHDGTW 120
  121 RETTTRTVDT PSGLERRVVE HTGVIDDH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [149-249]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRKWELENIV LEKGHTGLGF SITGGMDQPT EDGDTSIYVT NIIEGGAALA DGRMRKNDII  60
   61 TAVNNTNCEN VKHEVAVNAL KSSGNVVSLS LKRRKDEAFL P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.221849
Match: 2awxA
Description: No description for 2awxA was found.

Predicted Domain #3
Region A:
Residues: [250-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGGNFGGSTS YLRSGVTPSV SAGNLQHAIH SPSAPIHPPP PPPVHHGSLS QLSVGQYRST  60
   61 RPNTSVIDLV KGARGLGFSI AGGQGNEHVK GDTDIYVTKI IEEGAAELDG RLRVGDKILE 120
  121 VDHHSLINTT HENAVNVLNS LLT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 1vaeA
Description: Solution structure of the PDZ domain of mouse Rhophilin-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.566291652083235 bayes_pls_golite062009
protein binding 0.52823753548825 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle