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View Structure Prediction Details

Protein: CE33606
Organism: Caenorhabditis elegans
Length: 420 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE33606.

Description E-value Query
Range
Subject
Range
PUR9_ALTMD - Bifunctional purine biosynthesis protein PurH OS=Alteromonas macleodii (strain DSM 17117 / Deep ecot...
PUR9_ALTMD - Bifunctional purine biosynthesis protein PurH OS=Alteromonas mediterranea (strain DSM 17117 / CIP 11...
494.0 [0..3] [420..144]

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Predicted Domain #1
Region A:
Residues: [1-420]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIKVLNGSP GYINILDGLN GWQLVKELSD ATKMPAAASF KHVSPAGAAV GLPLNETEAA  60
   61 CCMVSDLPID TKKPSLAAAY ARAREQDWMI ADRLQRIAPS IGADRMSSFG DFIALSEKCD 120
  121 ELTAKIINRE VSDGVVAPDF DPAALSLLAK KKNGNYCVLK INPNYLPSET EERTVFGLRL 180
  181 RQKRNNAVIN AETFNNVVGS ANEVSDIRSL QIFKKHFMLS FLQNFHKYNC IKKSLFQLNK 240
  241 QAIDDLIVAT IALKYAQSNS VCFAHRGQVI GMGAGQQSRI HCTRLAGDKA MNWWLRQHPT 300
  301 VLSLPWKNAI KRSEKSNAID VLCSGVLGSE IAIDQWQQYF NEPVEPLAED DRKQWLSQQT 360
  361 GVVMSSDAFL PFRDNVDCAK QFGVSYVAHP GGSVRDDDIK EACDEHGITL IHTGLRLFHH 420
  421 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 111.0
Match: 1p4rA
Description: Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.177505784657 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle