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View Structure Prediction Details

Protein: syd-1
Organism: Caenorhabditis elegans
Length: 721 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for syd-1.

Description E-value Query
Range
Subject
Range
syd-1 - transcriptional activator HAP4 and regulatory domain of BCR and P85A status:Confirmed UniProt:Q86NH1...
413.0 [0..1] [721..267]

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Predicted Domain #1
Region A:
Residues: [1-210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRNATTSSTL RTHASTSSPR NHFAPRLVNG HSHSIGVPSA STTSHDHQYQ RFASEPSDSV  60
   61 SRTARVPPPR LASATVRRTE SFNSAPGVST SAPMYTLPRS STAVPPPDIL GSIPYSARDP 120
  121 LMRSSADLPY DPMTGRLSSS VPTDPLLSRS LCSPILPRTL RQANDSNKSN SLPRRRIMTG 180
  181 GRNVKWRNDV VSTSDLCGEE SDGAISAPEY 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [211-721]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSPPFSRLTQ QQQFRLSNGS PGRTVNDIFS AAEYRNWAGP YDPRGMYGPF PPGQRATRWS  60
   61 HTYGEQRAPR TSSLPGRTVL AQSLVGSPVL PRHPPPIVQD RPSAVFDRYH VSPLMNRRAP 120
  121 LRAAGPGINV DRLSVSSLTG ILYVHIVEGR GLKIPEKQKG LTEEMYCVLE VDEQHRARTG 180
  181 VSTIEQKFKW RETFHIDVVN ATVSNFFVYS WHPQFRHKLC HKGSLKLLEA FVVDQLNDDR 240
  241 VFALNLEPRG QLIVRIGFHD LQAVFRRTVN PRLNGVFGIS LSRLVQRERR DTPIVLTRLI 300
  301 QEIEKRGVDY SGLYVLCGSV EKKKMLRAEL ESNPLGTELA AESIPDTNVI ACLIKDFLRE 360
  361 LPEPLISPQI HGMLLEAASV ALPNDVQTNR HLVLKIIDCL QLSAKNCLLL VLDHLSTVLC 420
  421 SSPHNGLTPT RLSLIFAPLL FFCLDTFSPY TISPTSKMAA VRTLDINQAS SSLQMILSIW 480
  481 PSRVNSESGS DSPATTCQKG GVIAYVSESQ C

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.221849
Match: 1xa6A
Description: Crystal Structure of the Human Beta2-Chimaerin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
enzyme activator activity 0.53004209819211 bayes_pls_golite062009
GTPase activator activity 0.528693496432149 bayes_pls_golite062009
binding 0.0980674097362609 bayes_pls_golite062009
Ras GTPase activator activity 0.0454578418356197 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle