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View Structure Prediction Details

Protein: nuo-5
Organism: Caenorhabditis elegans
Length: 634 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nuo-5.

Description E-value Query
Range
Subject
Range
gi|78044647, gi|... - gi|78044647|ref|YP_359587.1| NAD-dependent formate dehydrogenase, alpha subunit, selenocysteine-cont...
533.0 [0..32] [630..4]

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Predicted Domain #1
Region A:
Residues: [1-634]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHRVGGQIVR GVSKAQQKRS LSVAAPAPPK KVEVFIDDKK VLVDPGMTIL QACALVGVDI  60
   61 PRFCYHDRLS IAGNCRMCLV EVEKSVKPVA SCAMPVMNGM KVKTNSDFVK KAREGVMEFM 120
  121 LNNHPLDCPI CDQGGECDLQ DQAMNFGSDR GRLQSRFDGK RALEDKNIGP LVKTVMTRCI 180
  181 QCTRCVRFAN EVAAFPDFGT TGRGQDLQIG TYVEKFFASE LSGNIIDICP VGALTSKQYA 240
  241 FTARPWETRK TESVDVMDAT GSNIVLSHRT GELLRVIPKI NDDINEEWIG DQSRFAVDGL 300
  301 KVQRLLTPMI RGADGQLKPA TWEEALFTVA AKLRETPAEQ KAAVAGGLND VESLVALKDL 360
  361 FNRFNSENVM TEEEFPDVGS GGSDLRSNYV FNDGIASVEN ADAILLVGTN PRFEAPTLNA 420
  421 RIRKSFLYSD VQVGVIGAET ELTYEYDYLG ASAKAIDEIL AGKGDFAKIL SSATTPLIIV 480
  481 GAQALKGEAG AALLGKLQQL ADKLGSGKEV KVLNVLQRWA GQAGALDVGY KAGTAGIRKT 540
  541 PIKFLYLLGA DEGKVTKANL DPSAFVVYQG HHGDAGAEMA DVVLPGAAYT EKEGTYVNTE 600
  601 GRSQRCASGK AKKKLDLSIF WQRKSNNFGF FQRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.0
Match: 2fug3
Description: Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity 3.42905611129045 bayes_pls_golite062009
electron carrier activity 2.29892126091131 bayes_pls_golite062009
succinate dehydrogenase activity 2.17392875467497 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 2.00026555763397 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 1.9389275936249 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor 1.87673954208357 bayes_pls_golite062009
formate dehydrogenase activity 1.34526518541816 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 1.22033162240751 bayes_pls_golite062009
NADH dehydrogenase activity 1.11412439147941 bayes_pls_golite062009
binding 0.689656573625534 bayes_pls_golite062009
4 iron, 4 sulfur cluster binding 0.628123949302495 bayes_pls_golite062009
iron-sulfur cluster binding 0.5629744057246 bayes_pls_golite062009
metal cluster binding 0.5629744057246 bayes_pls_golite062009
oxidoreduction-driven active transmembrane transporter activity 0.300439488774121 bayes_pls_golite062009
catalytic activity 0.105119876745552 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 0.0921104166364124 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle