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View Structure Prediction Details

Protein: acr-16
Organism: Caenorhabditis elegans
Length: 480 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acr-16.

Description E-value Query
Range
Subject
Range
gi|73974924 - gi|73974924|ref|XP_539232.2| PREDICTED: similar to cholinergic receptor, nicotinic, alpha polypeptid...
415.0 [0..13] [478..95]

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Predicted Domain #1
Region A:
Residues: [1-325]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVCTLLISC AILAAPTLGS LQERRLYEDL MRNYNNLERP VANHSEPVTV HLKVALQQII  60
   61 DVDEKNQVVY VNAWLDYTWN DYNLVWDKAE YGNITDVRFP AGKIWKPDVL LYNSVDTNFD 120
  121 STYQTNMIVY STGLVHWVPP GIFKISCKID IQWFPFDEQK CFFKFGSWTY DGYKLDLQPA 180
  181 TGGFDISEYI SNGEWALPLT TVERNEKFYD CCPEPYPDVH FYLHMRRRTL YYGFNLIMPC 240
  241 ILTTLMTLLG FTLPPDAGEK ITLQITVLLS ICFFLSIVSE MSPPTSEAVP LLGIFFTCCM 300
  301 IVVTASTVFT VYVLNLHYRT PETHD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.522879
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [326-480]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPWTRNLLL YWIPWILRMK RPGHNLTYAS LPSLFSTKPN RHSESLIRNI KDNEHSLSRA  60
   61 NSFDADCRLN QYIMTQSVSN GLTSLGSIPS TMISSNGTTT DVSQQATLLI LHRIYHELKI 120
  121 VTKRMIEGDK EEQACNNWKF AAMVRTYISR KIENF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.69897
Match: 1oedB
Description: Acetylcholine receptor protein, beta chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle