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View Structure Prediction Details

Protein: kcnl-2
Organism: Caenorhabditis elegans
Length: 672 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for kcnl-2.

Description E-value Query
Range
Subject
Range
kcnl-2 - status:Partially_confirmed UniProt:Q8I4G5 protein_id:CAD56594.1
373.0 [0..1] [653..1]

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Predicted Domain #1
Region A:
Residues: [1-105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGSPVADNP DDPLLNGSSA PKSILRAPRL TAAPKQLSFD VPASPTPTAK SSCVSTSGSY  60
   61 HMFERPNRLR AGKFSYGGLT SNHPHNQGHI QLTANGTPVF AYSGG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [106-585]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGGSCAVSPS SSARREDPSK WRLSDLKQRS NSESMFRNFD HELLADGGRR MSMAYLPSRE  60
   61 QALLRRILGP QGLSWISHDR ETASRKSVSI AYSNDLEAGG KGNGAIGDDS TVPLMDEKDD 120
  121 NSGGRLIRRE ILHEKRRHVS DRALAFAIMG IILMIIENEL RTAYVIRPGS SLSHLLKFFI 180
  181 IFTTTALLSF VGYFHVIEIQ LFMNANAADD WMVALSFRRT CQIGLELLIC MLCPLPIEFI 240
  241 APFMNDRFHD KTLYAVNVFL SIMMFFRLYW LCRVMLLHSR VFTDASSRSI AGLNRVNFNA 300
  301 RFILKTLMTI CPGTMLMIFT AFLWIIAGWI LRLCEREYMT PDKYNDINYV NSIWLVAITF 360
  361 LSVGYGDIVP KTNCGRSMAI VTGILGTCAS SMVVAVIARK LELTRAEKHV HNFMQDTQLT 420
  421 KQLKHSAANV LRETWFIFKF RKLVEKPDFG KIRKHQRKFL LAIYEMRRVR RDQRKLAENL 480
  481 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.30103
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [586-672]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSLGDVAKTS SNTYELVHDV HSTQEGLSLR ITAIEHQLSD ISRELSSLAE LLRGSNEQRK  60
   61 KSVVIGGESA PPTPQQILKR KIGELRV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.69897
Match: 2q0aA
Description: No description for 2q0aA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle