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View Structure Prediction Details

Protein: kcnl-2
Organism: Caenorhabditis elegans
Length: 655 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for kcnl-2.

Description E-value Query
Range
Subject
Range
kcnl-2 - status:Partially_confirmed UniProt:Q8I4G4 protein_id:CAD56595.1
399.0 [0..1] [649..1]

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Predicted Domain #1
Region A:
Residues: [1-104]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGSPVADNP DDPLLNGSSA PKSILRAPRL TAAPKQLSFD VPASPTPTAK SSCVSTSGSY  60
   61 HMFERPNRLR AGKFSYGGLT SNHPHNQGHI QLTANGTPVF AYSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [105-566]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGGGSCAVSP SSSARREDPS KWRLSDLKQR SNSESMFRNF DHELLADGGR RMSMAYLPSR  60
   61 EQALLRRILG PQGLSWISHD RETASRKSVS IAYSNDLEAG GKGNGAIGDD STVPLMDEKD 120
  121 DNSGGRLIRR EILHEKRRHV SDRALAFAIM GIILMIIENE LRTAYVIRPG SSLSHLLKFF 180
  181 IIFTTTALLS FVGYFHVIEI QLFMNANAAD DWMVALSFRR TCQIGLELLI CMLCPLPIEF 240
  241 IAPFMNDRFH DKTLYAVNVF LSIMMFFRLY WLCRVMLLHS RVFTDASSRS IAGLNRVNFN 300
  301 ARFILKTLMT ICPGTMLMIF TAFLWIIAGW ILRLCEREYM TPDKYNDINY VNSIWLVAIT 360
  361 FLSVGYGDIV PKTNCGRSMA IVTGILGTCA SSMVVAVIAR KLELTRAEKH VHNFMQDTQL 420
  421 TKQLKHSAAN VLRETWFIFK FRKLVEKPDF GKIRKHQRKF LL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.69897
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [567-655]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIYEMRRVRR DQRKLAENLV SLGDVAKTSS NTYELVHDVH STQEGLSLRI TAIEHQLSDI  60
   61 SRELSSLAEL LRGSVIITSD QMSNERKVS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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