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View Structure Prediction Details

Protein: bbs-8
Organism: Caenorhabditis elegans
Length: 506 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for bbs-8.

Description E-value Query
Range
Subject
Range
gi|113475191, gi... - gi|113475191|ref|YP_721252.1| glycosyl transferase family protein [Trichodesmium erythraeum IMS101],...
354.0 [0..1] [506..73]

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Predicted Domain #1
Region A:
Residues: [1-436]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGESVIEFT GFIKACRLFR ENRLAEAEAV CTNLLRKNPL DQATWALKMQ CLSDSTYVDE  60
   61 LENEDMGLAE TFLDQNVIAP NARPGTSFAR PKTSAKGVNP ILRPTTNAGR PLSGVVRPQS 120
  121 SFKSGSMDQA VRTARTAKTA RAVSSTSARN MRLGTASMAA GADGEFVNLA RLNIDKYAAD 180
  181 PQVNRQLFEY VFYYLNDIRV AHQIAGTASK AAGFEDYYWK NQLAKCYLRL GMLQDATKQL 240
  241 QSSLEQKKLI ETFALLSKAY NRVDQPMAAL KTYSAGLEVF PENVTMLTGM ARVQEALGEY 300
  301 DESVKLYKRV LDAESNNIEA IACVATTYYY GGKPELAMRY YRRILQMGVS SPELFLNIGL 360
  361 CCMAAQQFDF ALSSILRAQS TMTDDVAADV WYNIGQILVD IGDLVSAARS FRIALSHDPD 420
  421 HSESLVNLGI LKHREG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.0
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.93197588899451 bayes_pls_golite062009
protein binding 1.65083457326273 bayes_pls_golite062009
signal sequence binding 0.76823910767502 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [437-506]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIDEARSLYS SATSKNPYMF EGNYNLGLVS FTQGKYHECR ELIEKALAAF PEHEHCKKIL  60
   61 NHLKPLYESI 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.522879
Match: 1na0A
Description: Designed protein cTPR3
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle