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View Structure Prediction Details

Protein: kcnl-1
Organism: Caenorhabditis elegans
Length: 792 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for kcnl-1.

Description E-value Query
Range
Subject
Range
kcnl-1 - status:Confirmed UniProt:Q8I0J0 protein_id:CAD54171.1
462.0 [0..1] [792..1]

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Predicted Domain #1
Region A:
Residues: [1-186]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVRASSYCQ MDDRIPFLTP QLNSHSHSRL SAETEATSGN TLSSSLSTIP ITGQKFATPP  60
   61 NRVLVKGHTV STCSPRFGST SIPAPLDRRQ GRSCEFHTSD DDRHDRYDNP IAQMNSDDSE 120
  121 SPLNRRKTEP KRVLGTKNGS LSVTPGEKNE GRDRAFSMYS VSSDILRVSG YTQQFRSLLT 180
  181 ARFSPR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [187-623]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RESTPDVTVE APEDENKNDD RYVNGGVRFD NDVIEEGTAS GAASGGVGTP KKIAGFRRRQ  60
   61 SGYGIAISSD STAKMRCRLR KQLFIRRNKV CDISLFLAVL GLLLVIIDSE LTALSSSTGI 120
  121 TKDSPISIIL RSACVVSTFF LICCLINYHA IEVKIALIDS GADDWRVAFS TDRFIKMLIE 180
  181 VCVCMICPFP EIFSDGLMKM PYINADTRQV KMRDVPIDVL LSVPMFLRSY LVCRFMVLHS 240
  241 KQFQDAATRS IAALNRISMD FRFVIKTMMA DHPLRVLIVF TLSYWMCMSW MFTQCERYDG 300
  301 QLEVEHYYLN SMWFIMVTFM SIGYGDIVPN TYCGRCLSIT TGIVGAGVSS ALIAIISRKL 360
  361 ELSRAEKHVN NFMADSKLTN QRKNAAASVL QETWFIHKYK KALHKGDDLR LRHHQRRFLH 420
  421 SINEFRRIKW DQRKLQE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.69897
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [624-728]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGNSLLDVGK LHSDMHETLW EMHRTQDHFI SQIDVLTQKI MELQMTLNTR PPCCAPPTSS  60
   61 SNDAYFSTST QLGTVLPTVI PTIPLPPTQS PMLHASQSHR EPLQV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.221849
Match: 1p7bA
Description: Inward rectifier potassium channel Kirbac1.1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [729-792]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTTTTTSSDG LPRISVGSTS STATSASSGN GSLPQCTVDQ LSNCPTGGIY ATVTTPLISN  60
   61 FEEV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle