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View Structure Prediction Details

Protein: lgc-46
Organism: Caenorhabditis elegans
Length: 508 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lgc-46.

Description E-value Query
Range
Subject
Range
gi|73974924 - gi|73974924|ref|XP_539232.2| PREDICTED: similar to cholinergic receptor, nicotinic, alpha polypeptid...
343.0 [0..17] [507..56]

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Predicted Domain #1
Region A:
Residues: [1-381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQYLQFLSLV VLLLMCHARK SVYRRNSPSL RRLTRNYDWE VDEHGGLKPI INPAKVERAT  60
   61 KNCANDSFIL GTIMSNYNRH KIPGGQVDVE VEVWVQEITT ISDITSDFQL DIYIYETWYD 120
  121 PALNYAFMNP CKYNLSLNSV LLEKLWTPNS CFINSKTADI HKSPFPNIFL MIYANGTVWT 180
  181 NYRLKLQGPC IMDLTKFPFD NVTCSLTFES FNYNTDEVKM DWSVNGVQKM RDKMELADYE 240
  241 LVDIHKIRTT EEYPAGYWHE LTMSFEFKRR AGWYILQAYL PTYLTICISW ISFALGSKAI 300
  301 PARTMLGVNS LLAMTFQFGN IIRNLPRVSY VKAIDVWMLS CMTFVFCSLL ELAWVGYLSR 360
  361 EEEPTSAKCL QPSAQVAPKP C

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.045757
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [382-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPPPVQQNAN NSSVHRRQKQ PKNEEESALL SLRDNDYGYI PPGFGLNGNV ANAMKSFSSS  60
   61 CSCEPTNVVN LMLDEAETIP TSTSSSLSRK QRREILAHKI DSVSVFMFPF LFVLFNIAYW 120
  121 QHYLRGY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.30103
Match: 1oedB
Description: Acetylcholine receptor protein, beta chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle