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View Structure Prediction Details

Protein: gcy-32
Organism: Caenorhabditis elegans
Length: 646 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gcy-32.

Description E-value Query
Range
Subject
Range
CE44168 - WBGene00001552 locus:gcy-32 Soluble guanylate cyclase gcy-32 status:Confirmed UniProt:Q6DNF7 protein...
563.0 [0..1] [646..39]

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Predicted Domain #1
Region A:
Residues: [1-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNHYYSDTDT YVLVDSVSLV LKVTKDQVWE MYGGFLITYS MEIGWDELVR SMSPNLKGFL  60
   61 DNLDSLHYFI DHVVYKANLR GPSFRCEETP DGTLLLHYFT GRPGLYHIVK GVVKEVAKRV 120
  121 FDLDITLVVQ GRTQRSVHMN NGERVEEH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.522879
Match: 2o09A
Description: No description for 2o09A was found.

Predicted Domain #2
Region A:
Residues: [149-272]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VVFLINNLSE PRRDSEGSEV SLLTSTNANF PTIVDDTLGI SLDDFSKALP YHFVIDESCK  60
   61 LVQCGSELHN HIPNELLQPG TPILRIFEIN RPQIPLDFEN ICNFINAVFV LQVKTSPLKK 120
  121 KHMD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [273-405]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AMSQEELKQE METLDEDATN ELTQGHHLKL KGQMMLLASK KHIIYLCSPY VTSINELMQY  60
   61 GMRLTAMPLH DATRDLILLN QQRLSDVEVN LQLEANNEQL ETMTRELELE RQKTDSILKD 120
  121 MLPRRIAQQL LSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [406-646]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EHIEACEHEA TVMFCDLPAF QQAIPQCSPK DIVNMLNEIF RKLDRIVVIR GVYKVETVSD  60
   61 SYMAVSGIPD YTPEHAENMC HVALGMMWEA RSVIDPVSKT PFLLRIGIHS GTITAGVVGT 120
  121 VHPKYCLFGE TVTLASQMES LGMAGKIQCS KWAYQKAMET GRFEFSPRGR IDVKQRGLTE 180
  181 TYFLTRSLKK SIWEIIDHDR DINVNSIEGY EELETAIENA VTIKSALPRP DQRNSAACSI 240
  241 S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.39794
Match: 1yk9A
Description: Crystal structure of a mutant form of the mycobacterial adenylyl cyclase Rv1625c
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle