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View Structure Prediction Details

Protein: mig-10
Organism: Caenorhabditis elegans
Length: 667 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mig-10.

Description E-value Query
Range
Subject
Range
gi|56207000 - gi|56207000|emb|CAI24283.1| ortholog of human Ras association (RalGDS\/AF-6) and pleckstrin homology...
615.0 [0..17] [519..46]

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Predicted Domain #1
Region A:
Residues: [1-180]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTYDFPDPY PVQIRARPQV PPKPPIDTVR YSMNNIKESA DWQLDELLEE LEALETQLNS  60
   61 SNGGDQLLLG VSGIPASSSR ENVKSISTLP PPPPALSYHQ TPQQPQLLHH HNNHLGYQNG 120
  121 IHQITSINSA ASSCSSPDGD SAFGDSSSTE SSNNRCRNSA FSSNDSCRDS LNTPSPTQVS 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [181-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRNGELNAEE AKAQKIRQAL EKMKEAKVTK IFVKFFVEDG EALQLLIDER WTVADTLKQL  60
   61 AEKNHIALME DHCIVEEYPE LYIKRVYEDH EKVVENIQMW VQDSPNKLYF MRRPDKYAFI 120
  121 SRPELYLLTP KTSDHMEIPS GDQWTIDVKQ KFVSE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.30103
Match: 1wgrA
Description: Solution Structure of the RA Domain of Human Grb7 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.44703207958213 bayes_pls_golite062009
protein binding 1.14993629560865 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [336-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YFHREPVVPP EMEGFLYLKS DGRKSWKKHY FVLRPSGLYY APKSKKPTTK DLTCLMNLHS  60
   61 NQVYTGIGWE KKYKSPTPWC ISIKLTALQM KRSQFIKYIC AEDEMTFKKW LVALRIAK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.39794
Match: 1fgyA
Description: Grp1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.95118342902889 bayes_pls_golite062009
protein binding 1.40320448019588 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [454-532]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGAELLENYE RACQIRRETL GPASSMSAAS SSTAISEVPH SLSHHQRTPS VASSIQLSSH  60
   61 MMNNPTHPLS VNVRNQSPA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [533-667]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFSVNSCQQS HPSRTSAKLE IQYDEQPTGT IKRAPLDVLR RVSRASTSSP TIPQEESDSD  60
   61 EEFPAPPPVA SVMRMPPPVT PPKPCTPLTS KKAPPPPPKR SDTTKLQSAS PMAPAKNDLE 120
  121 AALARRREKM ATMEC

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.18
Match: 2j63A
Description: No description for 2j63A was found.

YRC Informatics Platform - Version 3.0
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