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View Structure Prediction Details

Protein: zyg-12
Organism: Caenorhabditis elegans
Length: 777 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for zyg-12.

Description E-value Query
Range
Subject
Range
gi|109488222 - gi|109488222|ref|XP_001077587.1| PREDICTED: similar to Myosin heavy chain, skeletal muscle, adult 2 ...
272.0 [0..5] [777..1241]

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Predicted Domain #1
Region A:
Residues: [1-206]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDLTNKESE SSDNGNSKYE DSIDGREVGT SKPFKEERSL EDLQADLADM AVWMEGLDAT  60
   61 KLPLNDPQLL CNGRAFSEVL HNVDKNFFTD GWLETMPENR TTNIMVFRSC TRKLWRKMFD 120
  121 YVNHINRTVV SSRWTDIHER IDGIYESDLP AMVNLGMAVV TLAHIGKNAK RFVDYSKALT 180
  181 STHKSMMSNV AKMVTTVIDE MPENPC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 1wixA
Description: The solution structure of RSGI RUH-026, conserved domain of HOOK1 protein from mouse
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.77302826695282 bayes_pls_golite062009
protein binding 1.34258839710246 bayes_pls_golite062009
microtubule binding 0.26034159312323 bayes_pls_golite062009
tubulin binding 0.11464228697646 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [207-358]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FHEISELHGS QSELNSLSES SGKLNGNGSS ERRSNADQIL VDAELEIERL RTETENQRKE  60
   61 IERLTKSFET AQHDMSSNSE SGDISILEKQ NEELRQKRRE LEEKNLELDA AVDQFKGIVF 120
  121 ELTNENDVLR RSDKERQRLQ TVLDAAQSDL DE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.91
Match: 1jchA
Description: Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [359-777]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WKTVANQYQK EAELSKQQDK EIKELLSQNK ALKSRLDHHV KSATLEDANK NGIAQLRTQV  60
   61 GGLTALNTEL KASLDSKKRC VEQLEIQLIQ HKEKVKELED RKDELIEERN RLENQLIFKE 120
  121 AVTPRSLHES MFEAGNLSFE PFSEKNTLPL EIENKRLTER IQELESLEPL KGELITLKSK 180
  181 NGVLEEEKLF ATKQIEELQQ QIEDLQENLL KNQEHASGDV VGLKIQLEKA EVEAQQMREA 240
  241 KMRAETNQAQ VDEILKKRTA ELEVNATALQ KAKAVIDELE YNSRPVSEDS MTSVQAFKEM 300
  301 KEENEKLRQK VEKLEIELNT VTQGFEQENR LLTSASHQQV LNRSIDEVMS MRAHAGSEEP 360
  361 QTLLDTQKMS GALPWRSLAS ETRRELPTAM ASILVLGFLV FIAWMFININ SALNAPPNA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

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