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View Structure Prediction Details

Protein: mes-2
Organism: Caenorhabditis elegans
Length: 773 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mes-2.

Description E-value Query
Range
Subject
Range
gi|2286221, gi|2... - ref|NP_496992.2| drosophila Enhancer of zeste/polycombeotic homolog essential for viability of the g...
658.0 [0..1] [773..1]

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Predicted Domain #1
Region A:
Residues: [1-76]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNSEPSTST PSGKTKKRGK KCETSMGKSK KSKNLPRFVK IQPIFSSEKI KETVCEQGIE  60
   61 ECKRMLKGHF NAIKDD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [77-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDIRVKDELD TDIKDWLKDA SSSVNEYRRR LQENLGEGRT IAKFSFKNCE KYEENDYKVS  60
   61 DSTVTWIKPD RTEEGDLMKK FRAPCSRIEV GDISPPMIYW VPIEQSVATP DQLRLTHMPY 120
  121 FGDGIDDGNI YEHLIDMFPD GIHGFSDNWS YVNDWILYKL CRAALKDYQG SPDVFYYTLY 180
  181 RLWPNKSSQR EFSSAFPVLC ENFAEKGFDP SSLEPWKKTK IAEGAQNLRN PTCYACLAYT 240
  241 CAIHGFKAEI PIEFPNGEFY NAMLPLPNNP ENDGK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [352-456]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCSGNCWKSV TMKEVSEVLV PDSEEILQKE VKIYFMKSRI AKMPIEDGAL IVNIYVFNTY  60
   61 IPFCEFVKKY VDEDDEESKI RSCRDAYHLM MSMAENVSAR RLKMG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [457-773]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPSNRLSIKD RVNNFRRNQL SQEKAKRKLR HDSLRIQALR DGLDAEKLIR EDDMRDSQRN  60
   61 SEKVRMTAVT PITACRHAGP CNATAENCAC RENGVCSYMC KCDINCSQRF PGCNCAAGQC 120
  121 YTKACQCYRA NWECNPMTCN MCKCDAIDSN IIKCRNFGMT RMIQKRTYCG PSKIAGNGLF 180
  181 LLEPAEKDEF ITEYTGERIS DDEAERRGAI YDRYQCSYIF NIETGGAIDS YKIGNLARFA 240
  241 NHDSKNPTCY ARTMVVAGEH RIGFYAKRRL EISEELTFDY SYSGEHQIAF RMVQTKERSE 300
  301 KPSRPKSQKL SKPMTSE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.0
Match: 2igqA
Description: No description for 2igqA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle