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View Structure Prediction Details

Protein: unc-43
Organism: Caenorhabditis elegans
Length: 533 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-43.

Description E-value Query
Range
Subject
Range
KCC2B_MOUSE, KCC... - (P28652) Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.1.123) (CaM-kinase I...
565.0 [0..4] [527..6]

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Predicted Domain #1
Region A:
Residues: [1-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMNASTKFSD NYDVKEELGK GAFSVVRRCV HKTTGLEFAA KIINTKKLSA RDFQKLEREA  60
   61 RICRKLQHPN IVRLHDSIQE ESFHYLVFDL VTGGELFEDI VAREFYSEAD ASHCIQQILE 120
  121 SIAYCHSNGI VHRDLKPENL LLASKAKGAA VKLADFGLAI EVNDSEAWHG FAGTPGYLSP 180
  181 EVLKKDPYSK PVDIWACGVI LYILLVGYPP FWDEDQHRLY AQIKAGAYDY PSPEWDTVTP 240
  241 EAKSLIDSML TVNPKKRITA DQALKVPWIC NRERVASAIH RQDTVDCLKK FNARRKLKAA 300
  301 ISAVKMVTRM SGVLRTSDST GSVASNGSTT HDASQVAGTS SQPTSPAAEG AILTTMIATR 360
  361 NLSNLGRNLL NKKEQGPPST IKESSESSQT I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 92.045757
Match: 2bdwA
Description: Crystal Structure of the Auto-Inhibited Kinase Domain of Calcium/Calmodulin Activated Kinase II
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [392-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDNDSEKAQK QDIVRVTQTL LDAISCKDFE TYTRLCDTSM TCFEPEALGN LIEGIEFHRF  60
   61 YFDGNRKNQV HTTMLNPNVH IIGEDAACVA YVKLTQFLDR NGEAHTRQSQ ESRVWSKKQG 120
  121 RWVCVHVHRS TQPSTNTTVS EF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.221849
Match: 2f86B
Description: The Association Domain of C. elegans CaMKII
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle