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View Structure Prediction Details

Protein: frm-4
Organism: Caenorhabditis elegans
Length: 643 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for frm-4.

Description E-value Query
Range
Subject
Range
frm-4 - status:Confirmed UniProt:P91092 protein_id:AAD32269.1
450.0 [0..1] [643..1]

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Predicted Domain #1
Region A:
Residues: [1-406]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQNNTSSSF LGRLTTSTRS SFMSPKDVRC NVHLLHDSDI IGNEFPRTQS AQTILDYVCQ  60
   61 LKHIQEKDFL GLRYQDHHKH RYWLDLTRSI NHVVKNFKKE IKKVGKTESM TLHLRFRYYP 120
  121 SDPARLRDPN LRYQLFVQLQ RDLLHGRLYC PTSSAAELAA LILQAQLGDY NEEKHVGNYV 180
  181 SGYKLLLKQT PKLEERIANN HKELKGKSSE SAELEFLEKA SQLDTYAFDP YTIKEPHDTL 240
  241 PVYIGASCKG ILIYTGQSRT HNIDWSELVK VDYSGKEIRL TLSENYRGQI TAAGTPTGTL 300
  301 NGHGPGSPSI MDKSLTKKPL TLKYTCPSGQ FAKHLWIHIL SQQAFFNETS AQDVKLKFSK 360
  361 PRIPLLSRGS TFRFPSKRVY REIEEEDSKS ILFDKSIMET SAVMNE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.0
Match: 2he7A
Description: No description for 2he7A was found.

Predicted Domain #2
Region A:
Residues: [407-503]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTTSNENEES ILNCSTISAP LSSGSGVVRY DLLRQTPRVE QPWLKQNSLK VTTVHDNTAS  60
   61 SSSSPDNSET QNNNLSKITN LNLSIEREVS TSPSTSP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [504-643]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPIVHTQQHS DHNSQNLEKN GNGKLANGGG SGVDLGKKTV HTNGTTLICT EEKQDSILSM  60
   61 DESLTSKSLI SRIANTCFVF FLILLLIVAI VIVLFEKSED SAHNDFIESH RALSDLRHLY 120
  121 YEPTRHYVVE QYRKHFGAKI 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.09691
Match: 2cs5A
Description: Solution structure of PDZ domain of Protein tyrosine phosphatase, non-receptor type 4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.566291652083235 bayes_pls_golite062009
protein binding 0.52823753548825 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle