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View Structure Prediction Details

Protein: bre-1
Organism: Caenorhabditis elegans
Length: 384 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for bre-1.

Description E-value Query
Range
Subject
Range
gi|49529344, gi|... - gi|50083368|ref|YP_044878.1| dTDP-D-glucose-4,6-dehydratase [Acinetobacter sp. ADP1], gi|49529344|em...
317.0 [0..36] [379..2]

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Predicted Domain #1
Region A:
Residues: [1-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADQNAKIEG LEACIGMSHE VSTTPAAELA AFRARKVALI TGISGQDGSY LAELLLSKGY  60
   61 KVHGIIRRSS SFNTARIEHL YSNPITHHGD SSFSLHYGDM TDSSCLIKLI STIEPTEVYH 120
  121 LAAQSHVKVS FDLPEYTAEV DAVGTLRLLD AIHACRLTEK VRFYQASTSE LYGKVQEIPQ 180
  181 SEKTPFYPRS PYAVAKMYGY WIVVNYREAY NMFACNGILF NHESPRRGET FVTRKITRSV 240
  241 AKISLGQQES IELGNLSALR DWGHAREYVE AMWRILQHDS PDDFVIATGK QFSVREFCNL 300
  301 AFAEIGEVLQ WEGEGVEEVG KNKDGVIRVK VSPKYYRPTE VETLLGNAEK AKKTLGWEAK 360
  361 VTVPELVKEM VASDIILMKS NPMA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.221849
Match: 1t2aA
Description: Crystal structure of human GDP-D-mannose 4,6-dehydratase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
UDP-glucose 4-epimerase activity 2.13934644118967 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.03956654822048 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.82673050487418 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle