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View Structure Prediction Details

Protein: mpk-1
Organism: Caenorhabditis elegans
Length: 444 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mpk-1.

Description E-value Query
Range
Subject
Range
gi|433357, gi|32... - gi|433357|gb|AAA18956.1| Sur-1 MAP kinase, ref|NP_497847.2| mitogen-activated Protein Kinase, plays ...
413.0 [0..1] [444..1]

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Predicted Domain #1
Region A:
Residues: [1-77]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTWIPNNLC AQPTTRNAKP PSNGHPQATQ QQSAPGSLAY RNSSNIPNGA TNHVRQQKWQ  60
   61 YTRSGHRKMA DGEAVIS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [78-444]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVNNVEEVHG QLFEVAPRYV NLSYIGEGAY GMVASALDTI TRDRVAIKKI SPFEHQTFCQ  60
   61 RTLREIKILN RFKHENIINI QEIIRSETVD SLKDIYIVQC LMETDLYKLL KTQKLSNDHV 120
  121 CYFLYQILRG LKYIHSANVL HRDLKPSNLL LNTTCDLKIC DFGLARVTDP QTDHTGFLTE 180
  181 YVATRWYRAP EIMLNSKGYT KSIDVWSVGC ILAEMLSNRP LFPGKHYLDQ LNLILAVVGS 240
  241 PSNADLQCII NDKARSYLIS LPHKPKQPWA RLYPGADPRA LDLLDKMLTF NPHNRIDIEQ 300
  301 ALAHPYLEQY YDPGDEPVCE EPFTLEMEFD DLPKEKLKEL IWEEAEAHHR RMEAEAAARN 360
  361 NGGQNPV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.045757
Match: 1wzyA
Description: Crystal structure of human ERK2 complexed with a pyrazolopyridazine derivative
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle