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View Structure Prediction Details

Protein: let-756
Organism: Caenorhabditis elegans
Length: 425 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for let-756.

Description E-value Query
Range
Subject
Range
gi|25396669 - gi|25396669|pir||H88481 protein let-756 [imported] - Caenorhabditis elegans
255.0 [0..1] [274..1]

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Predicted Domain #1
Region A:
Residues: [1-196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVPAASSIV SYGGAATSNF LTTPVTPFLA GFYNSNFVTD RINSCAPYRV DRIRKQLQDE  60
   61 EENGYPPADD RRRGALFCRS GTWLEMLPIE NPDDGSTRVK VHGTKEESSK FSIVEFVSVA 120
  121 MSLVSIRGVE TKNFICMDPS GKLYATPSSN YSTECVFLEE MMENYYNLYA SCAYGDRFNP 180
  181 WYIELRRSGK PRRGPN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.522879
Match: 1ihkA
Description: Fibroblast growth factor 9, FGF9
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
fibroblast growth factor receptor binding 5.68976822724664 bayes_pls_golite062009
growth factor activity 5.6790632853895 bayes_pls_golite062009
receptor binding 4.8109037277027 bayes_pls_golite062009
cytokine activity 3.72907359340826 bayes_pls_golite062009
protein binding 2.99442649109752 bayes_pls_golite062009
binding 2.90110516688922 bayes_pls_golite062009
glycosaminoglycan binding 2.49177421879896 bayes_pls_golite062009
heparin binding 2.1616134585534 bayes_pls_golite062009
polysaccharide binding 1.81686028727894 bayes_pls_golite062009
interleukin-1 receptor binding 0.8084616632765 bayes_pls_golite062009
pattern binding 0.323275442862789 bayes_pls_golite062009
nerve growth factor receptor binding 0.308245352535379 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [197-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKKRRKASHF LVVHHDLDRL RSPVPNGNDV TDLVVASLFH QPPSHPLFRQ QTVTKPPNPH  60
   61 RISNLRAKVE MTNQAEKQRL LEEKKRRREK KKRRREDRLR KEEQIREARR QELKSLREEE 120
  121 LRRRYQQQQQ QQASTQTRYN RPQNPANPYP TYRPLPTRST VQSPRPAYNP YWQSPVTQAP 180
  181 HHNSHHHHHH HPRVSSSSDP QQRHQSQQHY LAQTVSNPNR QNVNYQRYP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.154902
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle