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View Structure Prediction Details

Protein: CE24433
Organism: Caenorhabditis elegans
Length: 251 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE24433.

Description E-value Query
Range
Subject
Range
gi|52218988, gi|... - gi|52218988|ref|NP_001004571.1| calpain 3 [Danio rerio], gi|51858544|gb|AAH81672.1| Calpain 3, (p94)...
260.0 [0..4] [237..167]

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Predicted Domain #1
Region A:
Residues: [1-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKQSIEEYA WMIGKQTWAA FIEKGFAKLF GSYKSLSAKP IDVAFRKLTG AFSKNYELRS  60
   61 FKNCDAVWDM IVEAHLAGFL LCTSKLSLDE ESAEYIFNST GIKQNHAYAI LNSVVFENHR 120
  121 LVQIGNTHAC DKWKELHKEW NSLHYFYNKF SSKLPRRPYI SHLDDMSFWM DIDQYCEHFS 180
  181 SLTVCEYRKD WKEIRFRQTN DLKQSRETEA LRMTVDRRCE LVVEVTDRVL AKIWVTRNRD 240
  241 TEVSFVKQDV K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.154902
Match: 1kfuL
Description: Calpain large subunit, C-terminal domain (domain IV); Calpain large subunit, middle domain (domain III); Calpain large subunit, catalytic domain (domain II)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.529663942126259 bayes_pls_golite062009
hydrolase activity 0.16837900182603 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle