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View Structure Prediction Details

Protein: rnp-6
Organism: Caenorhabditis elegans
Length: 749 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rnp-6.

Description E-value Query
Range
Subject
Range
gi|76689289 - gi|76689289|ref|XP_881630.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
333.0 [0..4] [482..94]

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Predicted Domain #1
Region A:
Residues: [1-94]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEENSADIEN RPVAAFRPAV SVPMPVLPQD GEVFVGPGGK KDAQKIGLGL SKLSSKRKDD  60
   61 IQMAKKYAMD ISIKQILLRQ QKQQQENQQR QQMY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.0
Match: 2g4bA
Description: No description for 2g4bA was found.

Predicted Domain #2
Region A:
Residues: [95-299]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQALSIMSRI YVGSISFEIR EDMLRRAFDP FGPIKSINMS WDPATGHHKT FAFVEYEVPE  60
   61 AALLAQESMN GQMLGGRNLK VNSMMFQEMR LPQNMPQAQP IIDMVQKDAK KYFRVYVSSV 120
  121 HPDLSETDLK SVFEAFGEIV KCQLARAPTG RGHRGFGYLE FNNLTSQSEA IAGMNMFDLG 180
  181 GQYLRVGKCV TPPDALTYLQ PASVS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.69897
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.10590295737522 bayes_pls_golite062009
nucleic acid binding 1.43479844212501 bayes_pls_golite062009
RNA binding 0.426544317458995 bayes_pls_golite062009
protein binding 0.303849616374798 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [300-388]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIPASVSVAC AAITAKVMAA EAAAGSSPKT PSESGGSRAA SPAPRAQSPA TPSSSLPTDI  60
   61 ENKAVISSPK KEPEEIEVPP LPPSAPDVV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [389-599]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDEPMEIEEE EEYTIPEEKP KPVAIVPPPG LAIPSLVAPP GLIAPTEIGI VVPNPSFLAQ  60
   61 QQQKIEEKIE EEEEARTERV KLSTSQRKKM KREKLNQMTF EEKMAQVLGQ QKAVQNQRMA 120
  121 DPVTFGALDD TVAWKDPSNE DQTSEDGKML AIMGPGRGGD NVASMALALM DGGSSLMLAN 180
  181 NAKAKEAAAA LALEPKKKKK VKEGKKIQPK L

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.02
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #5
Region A:
Residues: [600-749]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTAQALAAAA KAGEMSDALK NEVMNSEDAS LASQEGLEIR GNDARHLLMT KLMRTNRSNV  60
   61 IVLRNMVTPQ DIDEFLEGEI REECGKYGNV IDVVIANFAS SGLVKIFVKY SDSMQVDRAK 120
  121 AALDGRFFGG NTVKAEAYDQ ILFDHADYTG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.154902
Match: 1hl6A
Description: CG8781 protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.10590295737522 bayes_pls_golite062009
nucleic acid binding 1.43479844212501 bayes_pls_golite062009
RNA binding 0.426544317458995 bayes_pls_golite062009
protein binding 0.303849616374798 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle