YRC Public Data Repository - Protein Structure Prediction

Protein:	pen-2
Organism:	Caenorhabditis elegans
Length:	101 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pen-2.

Description	E-value	Query Range	Subject Range
gi\|47225578 - gi\|47225578\|emb\|CAG12061.1\| unnamed protein product [Tetraodon nigroviridis]	150.0	[0..1]	[99..1]
gi\|182890176, gi... - gi\|62204246\|gb\|AAH92674.1\| Presenilin enhancer 2 homolog [Danio rerio], gi\|182890176\|gb\|AAI64817.1\| ...	150.0	[0..1]	[99..1]
gi\|111305751, gi... - gi\|89266904\|emb\|CAJ82298.1\| presenilin enhancer 2 homolog (C. elegans) [Xenopus tropicalis], gi\|6285...	146.0	[0..1]	[99..1]
gi\|157111831, gi... - gi\|157111831\|ref\|XP_001651746.1\| presenilin enhancer, putative [Aedes aegypti], gi\|108878286\|gb\|EAT4...	144.0	[0..1]	[100..1]
gi\|52138949, gi\|... - gi\|76779902\|gb\|AAI06245.1\| LOC494701 protein [Xenopus laevis], gi\|52138949\|gb\|AAH82697.1\| LOC494701 ...	144.0	[0..1]	[99..1]
gi\|91084865 - gi\|91084865\|ref\|XP_968065.1\| PREDICTED: similar to CG33198-PA [Tribolium castaneum]	143.0	[0..1]	[99..1]
gi\|114052008, gi... - gi\|87248387\|gb\|ABD36246.1\| presenilin enhancer [Bombyx mori], gi\|114052008\|ref\|NP_001040205.1\| prese...	143.0	[0..1]	[100..1]
gi\|58389917, gi\|... - gi\|58389917\|ref\|XP_317362.2\| AGAP008094-PA [Anopheles gambiae str. PEST], gi\|55237589\|gb\|EAA12574.2\|... AGAP008094-PA - Gamma-secretase subunit PEN-2\|protein_coding\|3R:5631660:5632112:1\|gene:AGAP008094	142.0	[0..1]	[100..1]

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Predicted Domain #1

Region A:
Residues: [1-101]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDISKLTDVK KVDLCKKYFL IGACFLPLVW IVNTFWFFSD AFCKPINAHR RQIRKYVIAS  60
   61 IVGSIFWIIV LSAWEIFFQH YRAQGLVWTD FLTFVFPTGR V

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.928	a.7.16	Description not found.
View	Download	0.905	a.24.9	alpha-catenin/vinculin
View	Download	0.877	a.25.3	Description not found.
View	Download	0.854	a.25.1	Ferritin-like
View	Download	0.837	a.24.1	Apolipoprotein
View	Download	0.837	a.24.1	Apolipoprotein
View	Download	0.824	f.17.1	F1F0 ATP synthase subunit C
View	Download	0.785	a.47.2	t-snare proteins
View	Download	0.751	a.7.1	Spectrin repeat
View	Download	0.749	f.17.1	F1F0 ATP synthase subunit C
View	Download	0.572	a.23.1	HSC20 (HSCB), C-terminal oligomerisation domain
View	Download	0.464	a.159.3	Description not found.
View	Download	0.447	a.7.8	GAT domain
View	Download	0.433	a.27.1	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View	Download	0.359	a.23.1	HSC20 (HSCB), C-terminal oligomerisation domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits