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View Structure Prediction Details

Protein: acr-10
Organism: Caenorhabditis elegans
Length: 510 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acr-10.

Description E-value Query
Range
Subject
Range
gi|73992736 - gi|73992736|ref|XP_543097.2| PREDICTED: similar to Neuronal acetylcholine receptor protein, alpha-4 ...
396.0 [0..2] [505..137]

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Predicted Domain #1
Region A:
Residues: [1-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKFQDGQNQ IIEVNAWLKY VWMDYRLQWD PLQYDNITSI RFAGGENQIW RPDILLYNSA  60
   61 SEDFDSSFKS NEVVYNTGEV NWIPPGIFRA SCKMDITYFP FDDQVCYLKF GSWTYHGLAL 120
  121 DLSIIAEEDD SELSIDLSTY TPSGEWHLTK APAVKDVKYN SCCKEPYSTV TFYMFLRRRT 180
  181 LFYLFNIILP SLLISIMTLM GFCLPAHDMS EKIGYQTTIL LSICFFVTIV SEMTPPTSES 240
  241 VPLLGMFFSS LTLISSVSTA FTITVLNFRY RQVQNIHMHP IFYKVFLIWI PWLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.221849
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [295-413]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LMKRPGVFYK KRRATVQARE EISFFDNGDD DCCPKPPEFD YSLSIDSADT LPLPPRPKPL  60
   61 LKKMHRLVQH IHQSNFVLFK RSRRTSSSRQ KSRRRNSKSQ RRPLVLTKNV NKSHSLRSR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.30103
Match: 1oedA
Description: Acetylcholine receptor protein, alpha chain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [414-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RFTQFEKYIK KCIDDAKLRK NSTYSTYSMM IITYYRQIDE MLKLLNRRLD KQRKYLFKQE  60
   61 DWKFAAMALD RLCLLLITLL IVMCLFGMIL STPHFEP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.56
Match: 1oedE
Description: Acetylcholine receptor protein, gamma chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle