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View Structure Prediction Details

Protein: unc-11
Organism: Caenorhabditis elegans
Length: 467 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-11.

Description E-value Query
Range
Subject
Range
gi|5002224 - gi|5002224|gb|AAD37369.1|AF144261_1 AP180-like adaptor protein [Caenorhabditis elegans]
363.0 [0..1] [390..1]

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Predicted Domain #1
Region A:
Residues: [1-383]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTIEKALHQ PMPFTTGGQT ISDRLTAAKH SLAGSQLGKT ICKATTEEVM APKKKHLDYL  60
   61 LHCTNEPNVS IPSMANLLIE RTQNPNWTVV YKALITIHNI MCYGNERFSQ YLASCNTTFN 120
  121 LTAFVDKVGG AGGYDMSTHV RRYAKYIGEK INTYRMCAFD FCKVKRGRED GLLRTMHTDK 180
  181 LLKTIPILQN QIDALLEFSV TTSELNNGVI NCSFILLFRD LIRLFACYND GIINVLEKYF 240
  241 DMNKKQCRDA LDTYKSFLTR LDKVAEFLRV AESVGIDRGE IPDLTRAPAS LLEALEAHLI 300
  301 HLEGGKAPPP TQQHVAPHQF TTGFAFSQQP QPALGDAERQ RYIELEQERL RQFEDQKKSI 360
  361 NSANPFANDV ASAAPAPATS AAH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.69897
Match: 1hf8A
Description: Clathrin assembly lymphoid myeloid leukaemia protein, Calm
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.229007340928547 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [384-467]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QCIRLQWECI NNHLVLSQCG ILRWQHTVNN MDTDNLFHHN SNTKFNWFMQ RWLQRTLHKL  60
   61 NRPRPPQPIH LDYSLVVYFS LSLS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle