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View Structure Prediction Details

Protein: pde-6
Organism: Caenorhabditis elegans
Length: 760 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pde-6.

Description E-value Query
Range
Subject
Range
gi|114658666 - gi|114658666|ref|XP_001162527.1| PREDICTED: phosphodiesterase 8A isoform 1 [Pan troglodytes]
470.0 [0..39] [755..11]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDRSGVGGE EGEKSVLGAS AHSQAGRRQQ HTPAARRGAQ RAPAATAAAA SRPVFAMRWC  60
   61 CGGSYSENGG GGGGSRGAPP TPLLTVAATS SSTAHDTFGP MQVKMLKTAV IVTEGTGESV 120
  121 LLDSLRASGW ICTVSFPTQA TSDVESICPL AVFIDLRVPH 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [161-357]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSQIAKDVSS VSTEEVLIVS IAEKHISEKR RRALAQSNII HHVTWNTRDV VLFDYVGRLA  60
   61 NRIRALPALF AVLDETDQAV EICDEQRVVQ YVNRAYENVT GCIRSEVIGQ PESEMRRKSL 120
  121 PRARGEEERR RSCDWKFIRV PFANNSQFVY MKRSNTTGDT AAIFRDVSLK SLKSQTGGIE 180
  181 APISEVLTML RDVSARV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.045757
Match: 2pr5A
Description: No description for 2pr5A was found.

Predicted Domain #3
Region A:
Residues: [358-417]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGEPAQTIKD AMKVLSSHEL YAPSINRFRD ADRIATQYYD GLIRLHHPAR QRKRSVVDAH  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [418-760]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 REKRGSHGER RRVSADVKNA LENDNCWKFD ILHLEKVSDH HALSQVGMKV FERWKVCDVL  60
   61 GCSDDLLHRW ILSIEAHYHA GNTYHNATHA ADVLQATSFF LDSPSVAVHV NESHAVAALL 120
  121 AAAVHDLDHP GRGNAYLINT RQSLAILYND NSILENHHIA LAFQLTLQHN ANVNIFSSLS 180
  181 REEFIQMRHA MVEMVLATDI SRHFEYLAKF NKMHVTDVPE EQRDTNSLTI CDMLVKCADI 240
  241 SNPAREWGLC QRWAHRIVEE YFEQTREEKE KGLPVTMEVF DRNTCNVPIT QCGFIDMFAR 300
  301 EAFATFTEFA KLGELSDQLE SNYEKWKVMT SQWTPTHNTN LVL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 92.69897
Match: 1oynA
Description: Catalytic domain of cyclic nucleotide phosphodiesterase pde4d
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.540422983488568 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle