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View Structure Prediction Details

Protein: unc-60
Organism: Caenorhabditis elegans
Length: 152 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-60.

Description E-value Query
Range
Subject
Range
gi|48374972 - gi|48374972|gb|AAT42170.1| putative actin depolymerizing factor [Sorghum bicolor]
186.0 [0..2] [146..329]
ADF2_PETHY - Actin-depolymerizing factor 2 OS=Petunia hybrida GN=ADF2 PE=2 SV=1
178.0 [0..2] [148..5]
gi|84028521 - gi|84028521|gb|ABC49719.1| actin depolymerizing factor-like protein [Arachis hypogaea]
177.0 [0..2] [146..5]
ADF1_ARATH - Actin-depolymerizing factor 1 OS=Arabidopsis thaliana GN=ADF1 PE=1 SV=1
gi|195604826 - gi|195604826|gb|ACG24243.1| hypothetical protein [Zea mays]
175.0 [0..2] [146..5]
gi|92897576 - gi|92897576|gb|ABE93742.1| Actin-binding, cofilin/tropomyosin type [Medicago truncatula]
174.0 [0..2] [146..5]
gi|89212812 - gi|89212812|gb|ABD63906.1| actin depolymerizing factor 2 [Gossypium hirsutum]
174.0 [0..2] [146..5]
gi|38564721 - gi|38564721|gb|AAR23800.1| putative actin-depolymerizing factor 2 [Helianthus annuus]
174.0 [0..2] [146..5]
gi|106879609 - gi|106879609|emb|CAJ38388.1| actin-depolymerizing factor [Plantago major]
174.0 [0..3] [146..6]

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Predicted Domain #1
Region A:
Residues: [1-152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASGVKVDPS CKNAYDLLHN KHQHSYIIFK IDKNDTAIVV EKVGEKNAPY AEFVEEMKKL  60
   61 VEDGKECRYA AVDVEVTVQR QGAEGTSTLN KVIFVQYCPD NAPVRRRMLY ASSVRALKAS 120
  121 LGLESLFQVQ ASEMSDLDEK SVKSDLMSNQ RI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.30103
Match: 1f7sA
Description: Cofilin (actin depolymerizing factor, ADF)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 7.52071741004022 bayes_pls_golite062009
cytoskeletal protein binding 6.04859625643932 bayes_pls_golite062009
actin filament binding 5.45532510538573 bayes_pls_golite062009
binding 2.84811181543046 bayes_pls_golite062009
protein binding 1.87981807141519 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding 1.3406661967545 bayes_pls_golite062009
phosphatidylserine binding 0.588992286163708 bayes_pls_golite062009
structural constituent of cytoskeleton 0.482954032096802 bayes_pls_golite062009
actin monomer binding 0.224304003054399 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle