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View Structure Prediction Details

Protein: efl-1
Organism: Caenorhabditis elegans
Length: 342 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for efl-1.

Description E-value Query
Range
Subject
Range
gi|37590269 - gi|37590269|gb|AAH59262.1| E2f3 protein [Mus musculus]
298.0 [0..4] [340..34]

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Predicted Domain #1
Region A:
Residues: [1-136]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDSYNDMED PGFRQLSDME LQKALEMTKQ SSIKNNLMLG LDNELDFDFD FDEDEDLDQP  60
   61 QMGTRADKSL GLLAKRFIRM IQYSPYGRCD LNTAAEALNV RQKRRIYDIT NVLEGIGLIE 120
  121 KRSKNMIQWK GGDFML

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.69897
Match: 1cf7A
Description: Cell cycle transcription factor E2F-4
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [137-264]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVKEGKRQSA TTEEEDRMEQ LKAEIEQLNK EEELIEQRQR WLQQSLRNMT ESVENNKLSY  60
   61 VLRSQLAEIQ GSDLTIGIQT RVGTQVRLSD PEQVEIHGGP SWCYLKDPSG PLRAAIVSNH 120
  121 ELHDFVQR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.154902
Match: 2azeB
Description: Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [265-342]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERAKRPGEEH VDADAPDEMM DDSRYRNRRT INDDEMFGFE QKVPAMKHLE PPPASDDYVY  60
   61 SSTGDEYRGD SIVDLYGD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle